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https://hdl.handle.net/1822/5751
Título: | Performance of the DNA-citoliq liquid-based cytology system compared with conventional smears |
Autor(es): | Alves, Venâncio Avancini Ferreira Castelo, A. Filho, A. L. Vianna, M. R. Taromaru, Eliane Namiyama, Gislene Lörincz, A. Dôres, Gerson B. das |
Palavras-chave: | Liquid-based cytology DNA-Citoliq system Thin layer cytology Split-sample study Severe severe dyskaryosis HPV |
Data: | Abr-2006 |
Editora: | Blackwell Publishing |
Revista: | Cytopathology |
Citação: | "Cytopathology". ISSN 0956-5507. 17:2 (Apr. 2006) 86-93. |
Resumo(s): | To evaluate the performance of a new, manual, simplified liquid-based system, DNA-Citoliq (Digene Brasil), employed under routine conditions as compared to conventional smears collected from six collaborating private laboratories. Methods: A panel of cytopathologists, who served as the gold standard diagnosis, adjudicated discordant opinions. Results: Of 3206 pairs of slides considered valid for comparison, there were 3008 in full agreement (93.8%), 112 (3.5%) with one diagnostic category discrepancies, and 86 (2.7%) discordant cases. Among the 288 borderline+ by either method, DNA-Citoliq detected abnormalities in 243 (84.4%), and conventional smears (CS) detected abnormalities in 178 (61.8%) (McNemar test, P < 0.000), a 36.5% increased detection of borderline+ cases. Conclusions: For mild dyskaryosis, DNA-Citoliq detected 176 cases and CS 125 cases (McNemar test, P < 0.000); and for moderate+severe dyskaryosis 66 versus 32 cases respectively (McNemar test, P < 0.000). |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/5751 |
DOI: | 10.1111/j.1365-2303.2006.00279.x |
ISSN: | 0956-5507 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | ICVS - Artigos em revistas internacionais / Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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DNAcitoliqandconventional.pdf | 1,04 MB | Adobe PDF | Ver/Abrir |