Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/5751

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dc.contributor.authorAlves, Venâncio Avancini Ferreira-
dc.contributor.authorCastelo, A.-
dc.contributor.authorFilho, A. L.-
dc.contributor.authorVianna, M. R.-
dc.contributor.authorTaromaru, Eliane-
dc.contributor.authorNamiyama, Gislene-
dc.contributor.authorLörincz, A.-
dc.contributor.authorDôres, Gerson B. das-
dc.date.accessioned2006-11-06T17:15:31Z-
dc.date.available2006-11-06T17:15:31Z-
dc.date.issued2006-04-
dc.identifier.citation"Cytopathology". ISSN 0956-5507. 17:2 (Apr. 2006) 86-93.eng
dc.identifier.issn0956-5507eng
dc.identifier.urihttp://hdl.handle.net/1822/5751-
dc.description.abstractTo evaluate the performance of a new, manual, simplified liquid-based system, DNA-Citoliq (Digene Brasil), employed under routine conditions as compared to conventional smears collected from six collaborating private laboratories. Methods: A panel of cytopathologists, who served as the gold standard diagnosis, adjudicated discordant opinions. Results: Of 3206 pairs of slides considered valid for comparison, there were 3008 in full agreement (93.8%), 112 (3.5%) with one diagnostic category discrepancies, and 86 (2.7%) discordant cases. Among the 288 borderline+ by either method, DNA-Citoliq detected abnormalities in 243 (84.4%), and conventional smears (CS) detected abnormalities in 178 (61.8%) (McNemar test, P < 0.000), a 36.5% increased detection of borderline+ cases. Conclusions: For mild dyskaryosis, DNA-Citoliq detected 176 cases and CS 125 cases (McNemar test, P < 0.000); and for moderate+severe dyskaryosis 66 versus 32 cases respectively (McNemar test, P < 0.000).eng
dc.language.isoengeng
dc.publisherBlackwell Publishingeng
dc.rightsopenAccesseng
dc.subjectLiquid-based cytologyeng
dc.subjectDNA-Citoliq systemeng
dc.subjectThin layer cytologyeng
dc.subjectSplit-sample studyeng
dc.subjectSevereeng
dc.subjectsevere dyskaryosispor
dc.subjectHPVpor
dc.titlePerformance of the DNA-citoliq liquid-based cytology system compared with conventional smearseng
dc.typearticlepor
dc.peerreviewedyeseng
sdum.number2eng
sdum.pagination86–93eng
sdum.publicationstatuspublishedeng
sdum.volume17eng
oaire.citationStartPage86por
oaire.citationEndPage93por
oaire.citationIssue2por
oaire.citationVolume17por
dc.identifier.doi10.1111/j.1365-2303.2006.00279.xpor
dc.identifier.pmid16548993por
dc.subject.wosScience & Technologypor
sdum.journalCytopathologypor
Appears in Collections:ICVS - Artigos em Revistas Internacionais com Referee

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