Host-derived biomarkers for risk assessment of invasive fungal diseases

doi:10.1007/978-1-4939-6515-1_7

Utilize este identificador para referenciar este registo: https://hdl.handle.net/1822/48523

Título:	Host-derived biomarkers for risk assessment of invasive fungal diseases
Autor(es):	Cunha, Cristina Amorim Gonçalves, Samuel M. Carvalho, Agostinho Albérico Rodrigues
Palavras-chave:	Invasive fungal disease Single nucleotide polymorphism (SNP) Host biomarkers Long pentraxin 3 (PTX3) Antifungal immunity Immunocompromised patients Risk stratification Personalized medicine
Data:	1-Jan-2017
Editora:	Humana Press
Revista:	Methods in Molecular Biology
Citação:	Cunha, C., Gonçalves, S. M., & Carvalho, A. (2017). Host-Derived Biomarkers for Risk Assessment of Invasive Fungal Diseases. Human Fungal Pathogen Identification: Methods and Protocols, 153-165
Resumo(s):	Invasive fungal diseases are major complications associated with the treatment of hematologic malignancies. The integration of host-derived biomarkers into clinical processes to predict the risk and progression of fungal disease is a promising approach in immunocompromised patients. Recent insights into human antifungal immunity have highlighted the remarkable influence of host genetics in modulating susceptibility to infection. In this chapter, we describe protocols to examine human genetic variation and to assess its functional consequences using the pattern recognition receptor PTX3 as an example.
Tipo:	Capítulo de livro
Descrição:	Host-Derived Biomarkers for Risk Assessment of Invasive Fungal Diseases
URI:	https://hdl.handle.net/1822/48523
ISBN:	978-1-4939-6513-7
e-ISBN:	978-1-4939-6515-1
DOI:	10.1007/978-1-4939-6515-1_7
ISSN:	1064-3745
Versão da editora:	https://link.springer.com/protocol/10.1007/978-1-4939-6515-1_7
Arbitragem científica:	yes
Acesso:	Acesso aberto
Aparece nas coleções:	ICVS - Livros e capítulos de Livros / Books and book chapters