Host-derived biomarkers for risk assessment of invasive fungal diseases

doi:10.1007/978-1-4939-6515-1_7

Utilize este identificador para referenciar este registo: https://hdl.handle.net/1822/48523

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Campo DC	Valor	Idioma
dc.contributor.author	Cunha, Cristina Amorim	por
dc.contributor.author	Gonçalves, Samuel M.	por
dc.contributor.author	Carvalho, Agostinho Albérico Rodrigues	por
dc.date.accessioned	2017-12-21T16:36:59Z	-
dc.date.available	2017-12-21T16:36:59Z	-
dc.date.issued	2017-01-01	-
dc.identifier.citation	Cunha, C., Gonçalves, S. M., & Carvalho, A. (2017). Host-Derived Biomarkers for Risk Assessment of Invasive Fungal Diseases. Human Fungal Pathogen Identification: Methods and Protocols, 153-165	por
dc.identifier.isbn	978-1-4939-6513-7	-
dc.identifier.issn	1064-3745	-
dc.identifier.uri	https://hdl.handle.net/1822/48523	-
dc.description	Host-Derived Biomarkers for Risk Assessment of Invasive Fungal Diseases	por
dc.description.abstract	Invasive fungal diseases are major complications associated with the treatment of hematologic malignancies. The integration of host-derived biomarkers into clinical processes to predict the risk and progression of fungal disease is a promising approach in immunocompromised patients. Recent insights into human antifungal immunity have highlighted the remarkable influence of host genetics in modulating susceptibility to infection. In this chapter, we describe protocols to examine human genetic variation and to assess its functional consequences using the pattern recognition receptor PTX3 as an example.	por
dc.description.sponsorship	European Society of Clinical Microbiology and Infectious Diseases (Research Grant 2012 to A.C.) and the Fundação para a Ciência e Tecnologia (FCT) (SFRH/BPD/96176/2013 to C.C. and IF/00735/2014 to A.C.). Further support was provided by FCT, cofunded by Programa Operacional Regional do Norte (ON.2—O Novo Norte), the Quadro de Referência Estratégico Nacional (QREN) through the Fundo Europeu de Desenvolvimento Regional (FEDER), and the Projeto Estratégico PEst-C/SAU/LA0026/2013	por
dc.language.iso	eng	por
dc.publisher	Humana Press	por
dc.relation	info:eu-repo/grantAgreement/FCT/COMPETE/133016/PT	por
dc.relation	info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F96176%2F2013/PT	por
dc.rights	openAccess	por
dc.subject	Invasive fungal disease	por
dc.subject	Single nucleotide polymorphism (SNP)	por
dc.subject	Host biomarkers	por
dc.subject	Long pentraxin 3 (PTX3)	por
dc.subject	Antifungal immunity	por
dc.subject	Immunocompromised patients	por
dc.subject	Risk stratification	por
dc.subject	Personalized medicine	por
dc.title	Host-derived biomarkers for risk assessment of invasive fungal diseases	por
dc.type	bookPart	por
dc.peerreviewed	yes	por
dc.relation.publisherversion	https://link.springer.com/protocol/10.1007/978-1-4939-6515-1_7	por
oaire.citationStartPage	153	por
oaire.citationEndPage	165	por
oaire.citationConferencePlace	New York, USA	por
oaire.citationVolume	1508	por
dc.date.updated	2017-12-15T17:21:02Z	-
dc.identifier.doi	10.1007/978-1-4939-6515-1_7	por
dc.identifier.eisbn	978-1-4939-6515-1	-
dc.identifier.pmid	27837502	por
dc.subject.fos	Ciências Médicas::Medicina Básica	por
dc.description.publicationversion	info:eu-repo/semantics/publishedVersion	por
dc.subject.wos	Science & Technology	por
sdum.journal	Methods in Molecular Biology	por
sdum.conferencePublication	HUMAN FUNGAL PATHOGEN IDENTIFICATION: METHODS AND PROTOCOLS	por
sdum.bookTitle	Human Fungal Pathogen Identification: Methods and Protocols	por
Aparece nas coleções:	ICVS - Livros e capítulos de Livros / Books and book chapters