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https://hdl.handle.net/1822/40521
Título: | The diagnostic and prognostic role of liquid-based cytology: are we ready to monitor therapy and resistance? |
Autor(es): | Rossi, Esther Diana Bizzarro, Tommaso Longatto Filho, Adhemar Gerhard, Rene Schmitt, Fernando |
Palavras-chave: | Effusions Immunocytochemistry Liquid-based cytology Malignancy Molecular analysis Nodular lesions targeted therapies |
Data: | 2015 |
Editora: | Taylor and Francis |
Revista: | Expert Review of Anticancer Therapy |
Citação: | Rossi, E. D., Bizzarro, T., Longatto-Filho, A., Gerhard, R., & Schmitt, F. (2015). The diagnostic and prognostic role of liquid-based cytology: are we ready to monitor therapy and resistance? Expert Review of Anticancer Therapy, 15(8), 911-921. doi: 10.1586/14737140.2015.1053874 |
Resumo(s): | Here, we evaluate the diagnostic and prognostic role of liquid-based cytology (LBC) in different body lesions, including thyroid, lung, effusions and malignant breast lesions. LBC has gained consensus after being applied to both non-gynecologic and fine-needle aspiration cytology. Although some remain sceptical regarding the diagnostic efficacy of LBC, mainly when used alone, in recent years, good results have been obtained as long as it showed a high diagnostic accuracy. Here, we discuss the additional possibility of storing material for the application of ancillary techniques (immunocytochemistry–molecular analysis) with several diagnostic and prognostic advantages, which may pave the way for the challenging evaluation of both monitoring responses to treatment and resistance to targeted therapies in thyroid, lung, breast carcinoma or malignant effusions. Furthermore, it provides the use of several molecular spots as specific targets for personalized therapy. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/40521 |
DOI: | 10.1586/14737140.2015.1053874 |
ISSN: | 1473-7140 1744-8328 |
Versão da editora: | http://www.tandfonline.com/doi/abs/10.1586/14737140.2015.1053874?journalCode=iery20 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | ICVS - Artigos em revistas internacionais / Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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10.1586@14737140.2015.1053874.pdf | 238,09 kB | Adobe PDF | Ver/Abrir |