Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/40521

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dc.contributor.authorRossi, Esther Dianapor
dc.contributor.authorBizzarro, Tommasopor
dc.contributor.authorLongatto Filho, Adhemarpor
dc.contributor.authorGerhard, Renepor
dc.contributor.authorSchmitt, Fernandopor
dc.date.accessioned2016-02-24T15:20:04Z-
dc.date.available2016-02-24T15:20:04Z-
dc.date.issued2015-
dc.identifier.citationRossi, E. D., Bizzarro, T., Longatto-Filho, A., Gerhard, R., & Schmitt, F. (2015). The diagnostic and prognostic role of liquid-based cytology: are we ready to monitor therapy and resistance? Expert Review of Anticancer Therapy, 15(8), 911-921. doi: 10.1586/14737140.2015.1053874-
dc.identifier.issn1473-7140por
dc.identifier.issn1744-8328por
dc.identifier.urihttp://hdl.handle.net/1822/40521-
dc.description.abstractHere, we evaluate the diagnostic and prognostic role of liquid-based cytology (LBC) in different body lesions, including thyroid, lung, effusions and malignant breast lesions. LBC has gained consensus after being applied to both non-gynecologic and fine-needle aspiration cytology. Although some remain sceptical regarding the diagnostic efficacy of LBC, mainly when used alone, in recent years, good results have been obtained as long as it showed a high diagnostic accuracy. Here, we discuss the additional possibility of storing material for the application of ancillary techniques (immunocytochemistry–molecular analysis) with several diagnostic and prognostic advantages, which may pave the way for the challenging evaluation of both monitoring responses to treatment and resistance to targeted therapies in thyroid, lung, breast carcinoma or malignant effusions. Furthermore, it provides the use of several molecular spots as specific targets for personalized therapy.por
dc.language.isoengpor
dc.publisherTaylor & Francispor
dc.rightsopenAccesspor
dc.subjectEffusionspor
dc.subjectImmunocytochemistrypor
dc.subjectLiquid-based cytologypor
dc.subjectMalignancypor
dc.subjectMolecular analysispor
dc.subjectNodular lesionspor
dc.subjecttargeted therapiespor
dc.titleThe diagnostic and prognostic role of liquid-based cytology: are we ready to monitor therapy and resistance?por
dc.typearticle-
dc.peerreviewedyespor
dc.relation.publisherversionhttp://www.tandfonline.com/doi/abs/10.1586/14737140.2015.1053874?journalCode=iery20por
sdum.publicationstatuspublishedpor
oaire.citationStartPage911por
oaire.citationEndPage921por
oaire.citationIssue8por
oaire.citationTitleExpert Review of Anticancer Therapypor
oaire.citationVolume15por
dc.date.updated2016-02-22T12:35:38Z-
dc.identifier.doi10.1586/14737140.2015.1053874por
dc.identifier.pmid26204907por
dc.subject.wosScience & Technologypor
sdum.journalExpert Review of Anticancer Therapypor
Appears in Collections:ICVS - Artigos em Revistas Internacionais com Referee

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