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|Title:||Williams Syndrome and memory : a neuroanatomic and cognitive approach|
Shenton, Martha E.
Gonçalves, Óscar F.
|Journal:||Journal of Autism and Developmental Disorders|
|Citation:||"Journal of Autism and Developmental Disorders." ISSN 0162-3257. 40:7 (Jul. 2010) 870–877.|
|Abstract(s):||Williams Syndrome (WS) is described as displaying a dissociation within memory systems. As the integrity of hippocampal formation (HF) is determinant for memory performance, we examined HF volumes and its association with memory measures in a group of WS and in a typically development group. A significantly reduced intracranial content was found in WS, despite no differences were observed for HF absolute volumes between groups. When volumes were normalized, left HF was increased in WS. Moreover, a lack of the normal right[left HF asymmetry was observed in WS. No positive correlations were found between volumetric and neurocognitive data in WS. In sum, a relative enlargement of HF and atypical patterns of asymmetry suggest abnormal brain development in WS|
|Access:||Restricted access (UMinho)|
|Appears in Collections:||CIPsi - Artigos (Papers)|
ICVS - Artigos em Revistas Internacionais com Referee
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