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TitleWilliams Syndrome and memory : a neuroanatomic and cognitive approach
Author(s)Sampaio, Adriana
Sousa, Nuno
Férnandez, Montse
Vasconcelos, Cristiana
Shenton, Martha E.
Gonçalves, Óscar F.
KeywordsWilliams Syndrome
Hippocampal formation
Memory performance
Issue dateJul-2010
JournalJournal of Autism and Developmental Disorders
Citation"Journal of Autism and Developmental Disorders." ISSN 0162-3257. 40:7 (Jul. 2010) 870–877.
Abstract(s)Williams Syndrome (WS) is described as displaying a dissociation within memory systems. As the integrity of hippocampal formation (HF) is determinant for memory performance, we examined HF volumes and its association with memory measures in a group of WS and in a typically development group. A significantly reduced intracranial content was found in WS, despite no differences were observed for HF absolute volumes between groups. When volumes were normalized, left HF was increased in WS. Moreover, a lack of the normal right[left HF asymmetry was observed in WS. No positive correlations were found between volumetric and neurocognitive data in WS. In sum, a relative enlargement of HF and atypical patterns of asymmetry suggest abnormal brain development in WS
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AccessRestricted access (UMinho)
Appears in Collections:CIPsi - Artigos (Papers)
ICVS - Artigos em Revistas Internacionais com Referee

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