Utilize este identificador para referenciar este registo: https://hdl.handle.net/1822/91792

TítuloChallenges with drug efficacy prediction of in vitro models of biofilms infecting cystic fibrosis airway
Autor(es)Sousa, Ana Margarida
Pereira, Maria Olívia
Palavras-chaveCystic fibrosis
Drug efficacy pediction
In vitro models
DataJun-2024
EditoraTaylor & Francis
RevistaExpert Opinion on Drug Discovery
CitaçãoSousa, Ana Margarida; Pereira, Maria Olívia, Challenges with drug efficacy prediction of in vitro models of biofilms infecting cystic fibrosis airway. Expert Opinion on Drug Discovery, 19(6), 635-638, 2024
Resumo(s)[Excerpt] Cystic fibrosis (CF) is a genetic disorder caused by a defect in the CF transmembrane conductance regulator gene, characterized by the accumulation of thick, sticky, and acidified sputum in the lungs. This abnormal buildup of sputum, rich in nutrients, and the defective mucociliary clearance render CF patients vulnerable to both acute and chronic bacterial infections of the airways. These infections lead to inflammation, declining lung function, respiratory failure, and premature death [1].
TipoEditorial em revista
URIhttps://hdl.handle.net/1822/91792
DOI10.1080/17460441.2024.2350567
ISSN1746-0441
Versão da editorahttps://www.tandfonline.com/journals/iedc20
Arbitragem científicayes
AcessoAcesso aberto
Aparece nas coleções:CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

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