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dc.contributor.authorUtagawa, Maria Lúcia-
dc.contributor.authorShirata, Neuza Kasumi-
dc.contributor.authorFerraz, Maria da Gloria Mattosinho de Castro-
dc.contributor.authorLoreto, Celso di-
dc.contributor.authorDall’ Agnol, Miria-
dc.contributor.authorLongatto Filho, Adhemar-
dc.descriptionProva tipográfica (In Press)-
dc.description.abstractObjectiveTo evaluate performance and viability of internal quality control QC) strategies in a public health laboratory of the state of Sao Paulo.Study DesignA retrospective study was per formed with 3 QC strategies to improve internal cytologic diagnoses: morphologic guided-list criteria (MGLC), 100% rapid-rescreening (100% RR) of negative slides ("turret" method) and 10% rescreening (10% R) of negative slides. Cases were examined at Adolfo Lutz Institute, Sao Paulo, Brazil, from 2002 to 2004. Histopathologic results, when available, were considered gold standard; cytologic consensus diagnosis was by 2 pathologists when histologic results were unavailable.ResultsMGLC selected 20.7% samples with cytologic atypias, 10% R selected 0.6% and RR selected 2.5%. Cytologic/histologic initial concordance was 57.4%, low-grade squamous intraepithelial lesion false negative rate was 34.9% and high-grade squamous intraepithelial lesion false negative rate was 12.2%. After diagnosis, consensus concordance was 97.2%.ConclusionThe 100% RR and 10% R QC strategies detected more false negative cases in liquid-based cytology than in conventional Pap smears. The 100% RR strategy reduced the false negative results and allowed evaluation of individual staff performance. The 10% R strategy did not offer significant results. We concluded that association of MGLC and 100% RR strategies might improve cytologic diagnostic quality.por
dc.publisherKarger Publisherspor
dc.subjectCytologic techniqueeng
dc.subjectPapanicolaou smeareng
dc.subjectQuality controleng
dc.titlePerformance of 3 methods for quality control for gynecologic cytology diagnoseseng
sdum.publicationstatusin publicationeng
dc.subject.wosScience & Technologypor
sdum.journalActa Cytologicapor
Appears in Collections:ICVS - Artigos em revistas internacionais / Papers in international journals

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