Genetic Determinants of Drug Resistance in Mycobacterium tuberculosis and Their Diagnostic Value

doi:10.1164/rccm.201510-2091OC

Utilize este identificador para referenciar este registo: https://hdl.handle.net/1822/62034

Título:	Genetic Determinants of Drug Resistance in Mycobacterium tuberculosis and Their Diagnostic Value
Autor(es):	Farhat, Maha R. Sultana, Razvan Iartchouk, Oleg Bozeman, Sam Galagan, James Sisk, Peter Stolte, Christian Nebenzahl-Guimaraes, Hanna Jacobson, Karen Sloutsky, Alexander Kaur, Devinder Posey, James Kreiswirth, Barry N. Kurepina, Natalia Rigouts, Leen Streicher, Elizabeth M. Victor, Tommie C. Warren, Robin M. van Soolingen, Dick Murray, Megan
Palavras-chave:	Antitubercular Agents Drug Resistance, Multiple, Bacterial Genes, Bacterial Humans Mutation Mycobacterium tuberculosis Sequence Analysis, DNA Tuberculosis, Multidrug-Resistant Molecular Diagnostic Techniques multidrug-resistant tuberculosis molecular diagnostics sensitivity and specificity
Data:	2016
Editora:	American Thoracic Society
Revista:	American Journal of Respiratory and Critical Care Medicine
Citação:	Farhat, M. R., Sultana, R., Iartchouk, O., Bozeman, et. al. (2016). Genetic determinants of drug resistance in Mycobacterium tuberculosis and their diagnostic value. American journal of respiratory and critical care medicine, 194(5), 621-630
Resumo(s):	The development of molecular diagnostics that detect both the presence of Mycobacterium tuberculosis in clinical samples and drug resistance-conferring mutations promises to revolutionize patient care and interrupt transmission by ensuring early diagnosis. However, these tools require the identification of genetic determinants of resistance to the full range of antituberculosis drugs.
Tipo:	Artigo
URI:	https://hdl.handle.net/1822/62034
DOI:	10.1164/rccm.201510-2091OC
ISSN:	1073-449X
e-ISSN:	1535-4970
Versão da editora:	https://www.atsjournals.org/doi/full/10.1164/rccm.201510-2091OC
Arbitragem científica:	yes
Acesso:	Acesso restrito UMinho
Aparece nas coleções:	ICVS - Artigos em revistas internacionais / Papers in international journals