Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/57861
Título: | Functional Roles of Astrocyte Calcium Elevations: From Synapses to Behavior |
Autor(es): | Gomes, Sónia Isabel Nunes Guerra Sousa, Nuno Pinto, Luísa Oliveira, João F. |
Palavras-chave: | Astrocyte Calcium Synapse Neural circuit Behavior |
Data: | Jan-2018 |
Editora: | Frontiers Media |
Revista: | Frontiers in Cellular Neuroscience |
Citação: | Guerra-Gomes, S., Sousa, N., Pinto, L., & Oliveira, J. F. (2018). Functional roles of astrocyte calcium elevations: from synapses to behavior. Frontiers in cellular neuroscience, 11, 427 |
Resumo(s): | Astrocytes are fundamental players in the regulation of synaptic transmission and plasticity. They display unique morphological and phenotypical features that allow to monitor and to dynamically respond to changes. One of the hallmarks of the astrocytic response is the generation of calcium elevations, which further affect downstream cellular processes. Technical advances in the field have allowed to spatially and to temporally quantify and qualify these elevations. However, the impact on brain function remains poorly understood. In this review, we discuss evidences of the functional impact of heterogeneous astrocytic calcium events in several brain regions, and their consequences in synapses, circuits, and behavior. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/57861 |
DOI: | 10.3389/fncel.2017.00427 |
ISSN: | 1662-5102 |
Versão da editora: | https://www.frontiersin.org/articles/10.3389/fncel.2017.00427/full |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | ICVS - Artigos em revistas internacionais / Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Guerra-Gomes et al. - 2018 - Functional Roles of Astrocyte Calcium Elevations .pdf | 1,03 MB | Adobe PDF | Ver/Abrir |