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TitleIn vitro genotoxicity assessment of a dextrin-based hydrogel for biomedical applications
Author(s)Pereira, Isabel
Fraga, Sónia
Silva, Susana
Teixeira, João Paulo
Gama, F. M.
Issue date24-Oct-2018
CitationPereira, Isabel; Fraga, Sónia; Silva, Susana; Teixeira, João Paulo; Gama, F. M., In vitro genotoxicity assessment of a dextrin-based hydrogel for biomedical applications. ICOETox 2018 - 4th International Congress on Occupational & Environmental Toxicology. Porto, Portugal, Oct 24-26, 127, 2018.
Abstract(s)[Excerpt] Hydrogels are three dimensional, crosslinked networks of hydrophilic polymers swollen with a large amount of water or biological fluids. Dextrin, a low-molecularweight carbohydrate composed by glucose residues, has been used to develop a novel fully resorbable and injectable hydrogel for biomedical applications. Dextrin was firstly oxidized (ODEX) to introduce aldehyde groups which then reticulate with adipic acid dihydrazide (ADH), forming the dextrin-based hydrogel (HG) [1]. The cross-linked ODEX is an in situ forming hydrogel, which displays a three-dimensional network with inter-connective pores, and is able to incorporate nanogels, cells and biomolecules for biomedical applications [1-3]. [...]
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AccessOpen access
Appears in Collections:CEB - Resumos em Livros de Atas / Abstracts in Proceedings

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