Utilize este identificador para referenciar este registo: https://hdl.handle.net/1822/56451

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Campo DCValorIdioma
dc.contributor.authorPereira, Isabelpor
dc.contributor.authorRodrigues, C.por
dc.contributor.authorRodrigues, A.por
dc.contributor.authorOliveira, M.por
dc.contributor.authorGama, F. M.por
dc.date.accessioned2018-10-21T15:35:14Z-
dc.date.issued2017-
dc.identifier.citationPereira, Isabel; Rodrigues, A.; Rodrigues, A.; Manuela Oliveira; Gama, F. M., 9 - Injectable hydrogels as a delivery system for bone regeneration. In Lígia Rodrigues, Manuel Mota, Bioinspired Materials for Medical Applications, Woodhead Publishing, 2017. ISBN: 978-0-08-100741-9, 241-271.por
dc.identifier.isbn978-0-08-100741-9por
dc.identifier.issn2049-9485por
dc.identifier.urihttps://hdl.handle.net/1822/56451-
dc.description.abstractThe worldwide incidence of bone disorders is increasing, mainly due to an ageing population. The lack of effective treatments is pushing the development of synthetic bone substitutes (SBSs). This chapter provides an overview of the currently available ceramic SBSs and describes the main advantages and limitations of commercially available ceramic-based injectable bone substitutes (IBSs), such as, bone cements and polymerceramic compositespastes and putties. The combination of injectable hydrogels and ceramic granules is emerging as a well-established trend. Particularly, in situ gelation hydrogels arise as a new IBSs generation. Herein, we present the recent progress in the development and application of hydrogel-based IBSs. Finally, the medical devices regulatory process is thoroughly discussed. Additionally, in view of the translation of IBSs into clinical practice, the main differences of the regulatory process in Europe and United States are highlighted.por
dc.description.sponsorship(undefined)por
dc.language.isoengpor
dc.publisherWoodhead Publishing Limitedpor
dc.rightsrestrictedAccesspor
dc.subjectBone regenerationpor
dc.subjectCeramicspor
dc.subjectSynthetic bone substitutepor
dc.subjectInjectable bone substitutepor
dc.subjectHydrogelpor
dc.subjectMedical devices regulatory processpor
dc.titleInjectable hydrogels as a delivery system for bone regenerationpor
dc.typebookPartpor
dc.peerreviewedyes-
dc.relation.publisherversionhttp://www.sciencedirect.com/science/book/9780081007419por
dc.commentsCEB45196por
oaire.citationStartPage241por
oaire.citationEndPage271por
oaire.citationVolume121por
dc.date.updated2018-10-21T11:42:53Z-
dc.identifier.doi10.1016/B978-0-08-100741-9.00009-7por
dc.description.publicationversioninfo:eu-repo/semantics/publishedVersionpor
dc.subject.wosScience & Technologypor
sdum.journalWoodhead Publishing Series in Biomaterialspor
sdum.conferencePublicationBIOINSPIRED MATERIALS FOR MEDICAL APPLICATIONSpor
sdum.bookTitleBioinspired Materials for Medical Applicationspor
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