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https://hdl.handle.net/1822/54444
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Campo DC | Valor | Idioma |
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dc.contributor.author | Silva, L. P. da | por |
dc.contributor.author | Cerqueira, M. T. | por |
dc.contributor.author | Correlo, V. M. | por |
dc.contributor.author | Reis, R. L. | por |
dc.contributor.author | Marques, A. P. | por |
dc.date.accessioned | 2018-04-18T12:37:16Z | - |
dc.date.available | 2018-04-18T12:37:16Z | - |
dc.date.issued | 2016 | - |
dc.date.submitted | 2016-05 | - |
dc.identifier.citation | da Silva L. P., Cerqueira M. T., Correlo V. M., Reis R. L., Marques A. P. (2016) Engineered hydrogel-based matrices for skin wound healing, Wound Healing Biomaterials, Vol. 2. | por |
dc.identifier.isbn | 9780081006061 | por |
dc.identifier.issn | 2049-9485 | por |
dc.identifier.uri | https://hdl.handle.net/1822/54444 | - |
dc.description.abstract | Hydrogels, due to their hygroscopic nature, have been widely used as wound dressings. Because hydrogels resemble native extracellular matrix (ECM), newer developments aim at recreating three-dimensional ECM-like microenvironments. In general, current hydrogels show limited molecular diffusion and cell binding sites. Spongy-like hydrogels, based on gellan gum polysaccharide, produced by a sequential advanced processing methodology, reunite the benefits of hydrogels along with the capacity to control specific cell behavior. These structures can be stored as dried networks that after re-hydration with a solution containing cells and/or bioactive molecules form the spongy-like hydrogels. Spongy-like hydrogels show improved physical stability, flexibility, viscoelasticity and facilitated manipulation in the incorporation of bioactive molecules and/or cells, in comparison to traditional hydrogels. These characteristics make spongy-like hydrogels attractive for skin regeneration purposes. In this chapter we present the work leading to spongy-like hydrogels, highlighting the possibility of fine-tuning their properties, effects of incorporating hyaluronic acid, stem cells and adult skin cells to meet the demands of specific wound types. | por |
dc.description.sponsorship | (undefined) | por |
dc.language.iso | eng | por |
dc.publisher | Elsevier | por |
dc.rights | openAccess | por |
dc.subject | Hydrogels | por |
dc.subject | Skin tissue engineering | por |
dc.subject | Spongy-like hydrogels | por |
dc.subject | Wound healing | por |
dc.title | Engineered hydrogel-based matrices for skin wound healing | por |
dc.type | bookPart | por |
dc.peerreviewed | yes | - |
dc.comments | http://3bs.uminho.pt/node/18724 | por |
sdum.publicationstatus | published | - |
oaire.citationStartPage | 227 | por |
oaire.citationEndPage | 250 | por |
oaire.citationTitle | Wound Healing Biomaterials | por |
oaire.citationVolume | 2 | - |
dc.date.updated | 2016-06-06T10:43:51Z | - |
dc.identifier.doi | 10.1016/B978-1-78242-456-7.00011-8 | por |
dc.description.publicationversion | info:eu-repo/semantics/publishedVersion | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Woodhead Publishing Series in Biomaterials | por |
sdum.conferencePublication | WOUND HEALING BIOMATERIALS, VOL 2: FUNCTIONAL BIOMATERIALS | por |
sdum.bookTitle | Wound Healing Biomaterials | por |
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Ficheiro | Descrição | Tamanho | Formato | |
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18724-Book_Chapter_Lsl.pdf | 2,12 MB | Adobe PDF | Ver/Abrir |