Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/49089

TitleCoupled variability in primary sensory areas and the hippocampus during spontaneous activity
Author(s)Vasconcelos, Nivaldo A. P. de
Cunha, Carina Isabel Soares
Rodrigues, Ana João
Ribeiro, Sidarta
Sousa, Nuno
Issue date10-Apr-2017
PublisherNature Publishing Group
JournalScientific Reports
CitationDe Vasconcelos, N. A., Soares-Cunha, C., Rodrigues, A. J., Ribeiro, S., & Sousa, N. (2017). Coupled variability in primary sensory areas and the hippocampus during spontaneous activity. Scientific Reports, 7
Abstract(s)The cerebral cortex is an anatomically divided and functionally specialized structure. It includes distinct areas, which work on different states over time. The structural features of spiking activity in sensory cortices have been characterized during spontaneous and evoked activity. However, the coordination among cortical and sub-cortical neurons during spontaneous activity across different states remains poorly characterized. We addressed this issue by studying the temporal coupling of spiking variability recorded from primary sensory cortices and hippocampus of anesthetized or freely behaving rats. During spontaneous activity, spiking variability was highly correlated across primary cortical sensory areas at both small and large spatial scales, whereas the cortico-hippocampal correlation was modest. This general pattern of spiking variability was observed under urethane anesthesia, as well as during waking, slow-wave sleep and rapid-eye-movement sleep, and was unchanged by novel stimulation. These results support the notion that primary sensory areas are strongly coupled during spontaneous activity.
Typearticle
URIhttp://hdl.handle.net/1822/49089
DOI10.1038/srep46077
ISSN2045-2322
Publisher versionhttps://www.nature.com/articles/srep46077
Peer-Reviewedyes
AccessopenAccess
Appears in Collections:ICVS - Artigos em Revistas Internacionais com Referee

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