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TitleEditorial: An omics perspective on fungal Infection: toward next-generation diagnosis and therapy
Author(s)Carvalho, Agostinho Albérico Rodrigues
Goldman, Gustavo H.
KeywordsOmics techniques
Fungal infection
Personalized healthcare
Antifungal therapeutics
Biomarker discovery
Issue date26-Jan-2017
PublisherFrontiers Media
JournalFrontiers in Microbiology
Abstract(s)[Excerpt] Fungal infections are estimated to occur in over a billion people each year, and evidence suggests the rate is increasing. Vaccines are unavailable, and despite progress in diagnosis and therapy, the management of fungal infections is a challenging endeavor associated with unacceptable mortality rates, particularly in immunocompromised hosts (Kontoyiannis et al., 2010; Pagano et al., 2010). Importantly, the risk of infection and its clinical outcome vary significantly even among patients with similar predisposing conditions (Carvalho et al., 2010). Concerns over excessive prescription of antifungals and the remarkable burden conveyed to healthcare systems have encouraged efforts to decipher the molecular and cellular causes underlying variable susceptibility to infection (Cunha and Carvalho, 2012).[...]
TypeJournal editorial
Publisher version
AccessOpen access
Appears in Collections:ICVS - Artigos em revistas internacionais / Papers in international journals

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