Please use this identifier to cite or link to this item: https://hdl.handle.net/1822/46115

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dc.contributor.authorVeloso, Sérgio R. S.por
dc.contributor.authorRodrigues, Ana Rita Oliveirapor
dc.contributor.authorMartins, J. A.por
dc.contributor.authorFerreira, Paula M. T.por
dc.contributor.authorCastanheira, Elisabete M. S.por
dc.date.accessioned2017-07-06T10:54:13Z-
dc.date.available2017-07-06T10:54:13Z-
dc.date.issued2017-07-
dc.identifier.urihttps://hdl.handle.net/1822/46115-
dc.description.abstractIn this work, superparamagnetic manganese ferrite (MnFe2O4) nanoparticles were successfully incorporated in self-assembled peptide-derived hydrogels. The new magnetogels were tested as nanocarriers for two fluorescent drugs, curcumin (an anticancer and neuroprotective drug) and a new antitumor thienopyridine derivative. Fluorescence-based techniques (fluorescence emission, FRET and fluorescence anisotropy) were used to assess incorporation of these drugs in the magnetogels and their transport towards models of biological membranes. It can be observed that the drug moves to the model membranes upon interaction of the drug-loaded magnetogels with membranes.por
dc.description.sponsorshipThis work was supported by the Portuguese Foundation for Science and Technology (FCT) in the framework of the Strategic Funding of CF-UM-UP (UID/FIS/04650/2013) and of CQ-UM (UID/QUI/00686/2013). FCT, POPH-QREN and FSE are acknowledged for the PhD grant of A.R.O. Rodrigues (SFRH/BD/90949/2012) and for financial support to MAP-Fis Joint Doctoral Programme.por
dc.language.isoengpor
dc.relationinfo:eu-repo/grantAgreement/FCT/5876/147414/PTpor
dc.relationinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F90949%2F2012/PTpor
dc.rightsopenAccesspor
dc.subjectMagnetic nanoparticlespor
dc.subjectHydrogelspor
dc.subjectDrug nanocarrierspor
dc.subjectTargeted therapypor
dc.titleNew magnetogels based on manganese ferrite nanoparticles and self-assembled peptide hydrogels as drug nanocarrierspor
dc.typeconferenceAbstractpor
dc.peerreviewedyespor
dc.relation.publisherversionhttp://www.nanax8.org/abstracts/NaNax-Posters/P-NaNax8_Veloso%20S%C3%A9rgio.pdfpor
oaire.citationConferenceDate03 July - 07 July 2017por
sdum.event.typeconferencepor
oaire.citationConferencePlaceBraga, Portugalpor
oaire.citationTitleNaNaX 8 - Nanoscience with Nanocrystals International Conference 2017por
dc.subject.fosCiências Médicas::Biotecnologia Médicapor
dc.subject.fosCiências Naturais::Ciências Físicaspor
dc.subject.fosCiências Naturais::Ciências Químicaspor
dc.subject.fosEngenharia e Tecnologia::Nanotecnologiapor
dc.description.publicationversioninfo:eu-repo/semantics/publishedVersionpor
Appears in Collections:CDF - FAMO - Comunicações/Communications (with refereeing)

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