New magnetogels based on manganese ferrite nanoparticles and self-assembled peptide hydrogels as drug nanocarriers

Utilize este identificador para referenciar este registo: https://hdl.handle.net/1822/46115

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Campo DC	Valor	Idioma
dc.contributor.author	Veloso, Sérgio R. S.	por
dc.contributor.author	Rodrigues, Ana Rita Oliveira	por
dc.contributor.author	Martins, J. A.	por
dc.contributor.author	Ferreira, Paula M. T.	por
dc.contributor.author	Castanheira, Elisabete M. S.	por
dc.date.accessioned	2017-07-06T10:54:13Z	-
dc.date.available	2017-07-06T10:54:13Z	-
dc.date.issued	2017-07	-
dc.identifier.uri	https://hdl.handle.net/1822/46115	-
dc.description.abstract	In this work, superparamagnetic manganese ferrite (MnFe2O4) nanoparticles were successfully incorporated in self-assembled peptide-derived hydrogels. The new magnetogels were tested as nanocarriers for two fluorescent drugs, curcumin (an anticancer and neuroprotective drug) and a new antitumor thienopyridine derivative. Fluorescence-based techniques (fluorescence emission, FRET and fluorescence anisotropy) were used to assess incorporation of these drugs in the magnetogels and their transport towards models of biological membranes. It can be observed that the drug moves to the model membranes upon interaction of the drug-loaded magnetogels with membranes.	por
dc.description.sponsorship	This work was supported by the Portuguese Foundation for Science and Technology (FCT) in the framework of the Strategic Funding of CF-UM-UP (UID/FIS/04650/2013) and of CQ-UM (UID/QUI/00686/2013). FCT, POPH-QREN and FSE are acknowledged for the PhD grant of A.R.O. Rodrigues (SFRH/BD/90949/2012) and for financial support to MAP-Fis Joint Doctoral Programme.	por
dc.language.iso	eng	por
dc.relation	info:eu-repo/grantAgreement/FCT/5876/147414/PT	por
dc.relation	info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F90949%2F2012/PT	por
dc.rights	openAccess	por
dc.subject	Magnetic nanoparticles	por
dc.subject	Hydrogels	por
dc.subject	Drug nanocarriers	por
dc.subject	Targeted therapy	por
dc.title	New magnetogels based on manganese ferrite nanoparticles and self-assembled peptide hydrogels as drug nanocarriers	por
dc.type	conferenceAbstract	por
dc.peerreviewed	yes	por
dc.relation.publisherversion	http://www.nanax8.org/abstracts/NaNax-Posters/P-NaNax8_Veloso%20S%C3%A9rgio.pdf	por
oaire.citationConferenceDate	03 July - 07 July 2017	por
sdum.event.type	conference	por
oaire.citationConferencePlace	Braga, Portugal	por
oaire.citationTitle	NaNaX 8 - Nanoscience with Nanocrystals International Conference 2017	por
dc.subject.fos	Ciências Médicas::Biotecnologia Médica	por
dc.subject.fos	Ciências Naturais::Ciências Físicas	por
dc.subject.fos	Ciências Naturais::Ciências Químicas	por
dc.subject.fos	Engenharia e Tecnologia::Nanotecnologia	por
dc.description.publicationversion	info:eu-repo/semantics/publishedVersion	por
Aparece nas coleções:	CDF - FAMO - Comunicações/Communications (with refereeing)

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