Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/29603

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dc.contributor.authorMaciel, P.-
dc.contributor.authorPinho, Teresa-
dc.contributor.authorLemos, C.-
dc.contributor.authorSousa, Alda-
dc.date.accessioned2014-07-09T11:26:46Z-
dc.date.available2014-07-09T11:26:46Z-
dc.date.issued2010-06-
dc.identifier.issn0022-0345por
dc.identifier.urihttp://hdl.handle.net/1822/29603-
dc.description.abstractIn spite of recent developments, data regarding the genes responsible for the less severe forms of hypodontia are still scarce and controversial. This study addressed the hypothesis that agenesis of maxillary lateral incisors (MLIA) is a distinct type of hypodontia, by evaluating its familial aggregation and the occurrence of other types of ageneses or microdontia in probands' relatives. Sixty-two probands with MLIA were identified, and information was collected on 142 first-degree relatives. Relative risk (RR) was calculated and compared by re-assessment of data previously published for the Swedish, Utah, and Israeli populations, for the same trait. A RR of 15 was obtained in the Portuguese, 16 in the Swedish, 12 in Utah, and 5 in the Israeli population. Our results support a significant familial aggregation of MLIA, show that MLIA almost never segregates with other forms of agenesis, and suggest that microdontia of maxillary lateral incisors is part of the same phenotype.por
dc.description.sponsorshipThe individuals who took part in this study are acknowledged. Carolina Lemos was the recipient of a PhD scholarship (FCT - SFRH/BD/17761/2004) and Teresa Pinho of a PhD scholarship from Instituto Superior de Ciencias da Saude Norte/CESPU. The other authors received no funding from any institution, department, or sponsor, other than salaries from the institutions with which they are affiliated.por
dc.language.isoengpor
dc.publisherSAGEpor
dc.rightsopenAccesspor
dc.subjectHypodontiapor
dc.subjectMicrodontiapor
dc.subjectMaxillary lateral incisorspor
dc.subjectRelative riskpor
dc.subjectFamilial aggregationpor
dc.titleFamilial aggregation of maxillary lateral incisor agenesispor
dc.typearticle-
dc.peerreviewedyespor
dc.relation.publisherversionhttp://jdr.sagepub.com/content/89/6/621por
sdum.publicationstatuspublishedpor
oaire.citationStartPage621por
oaire.citationEndPage625por
oaire.citationIssue6por
oaire.citationTitleJournal of Dental Research (JDR)por
oaire.citationVolume89por
dc.date.updated2014-06-13T12:42:01Z-
dc.identifier.doi10.1177/0022034510364486por
dc.identifier.pmid20400722por
dc.subject.wosScience & Technologypor
sdum.journalJournal of Dental Research (jdr)por
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