Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/29554
Título: | Influence of amygdaloid glutamatergic receptors on sensory and emotional pain-related behavior in the neuropathic rat |
Autor(es): | Ansah, Osei B. Bourbia, Nora Gonçalves, Leonor Almeida, Armando Pertovaara, Antti |
Palavras-chave: | Amygdal Aversive place-conditioning Descending pain modulation Emotional pain Mechanical pain sensibility Peripheral neuropathy Amygdala |
Data: | 2010 |
Editora: | Elsevier 1 |
Revista: | Behavioural Brain Research |
Resumo(s): | The role of amygdaloid glutamatergic receptors (GluRs) in maintenance of the sensory versus emotional component of neuropathic pain was studied by assessing monofilament-induced limb withdrawal response (sensory pain) and aversive place-conditioning behavior (emotional pain) following amygdaloid administration of various glutamatergic compounds in nerve-injured animals. The results indicate that endogenous activation of amygdaloid group I metabotropic GluRs, mGluR(1) and mGluR(5), and the NMDA-R contributes to maintenance of sensory and emotional components of neuropathic pain. The predominant effect by amygdaloid group I mGluRs was facilitation of emotional-like pain behavior. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/29554 |
DOI: | 10.1016/j.bbr.2010.01.021 |
ISSN: | 0166-4328 |
Versão da editora: | http://www.sciencedirect.com/science/article/pii/S0166432810000458 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | ICVS - Artigos em revistas internacionais / Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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ansah o_behav brain res 2010.pdf | 749,4 kB | Adobe PDF | Ver/Abrir |