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https://hdl.handle.net/1822/24364
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Campo DC | Valor | Idioma |
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dc.contributor.author | Dias, Oscar | - |
dc.contributor.author | Gombert, Andreas Karoly | - |
dc.contributor.author | Ferreira, Eugénio C. | - |
dc.contributor.author | Rocha, I. | - |
dc.date.accessioned | 2013-06-06T13:45:40Z | - |
dc.date.available | 2013-06-06T13:45:40Z | - |
dc.date.issued | 2013 | - |
dc.identifier.uri | https://hdl.handle.net/1822/24364 | - |
dc.description.abstract | The interest in Kluyveromyces lactis (K. lactis) has begun in academia due to its ability to metabolize the betaglycoside (1). Since then, this yeast has been considered a model organism for studies in genetics and physiology (2). This yeast had its genome sequenced back in 2004 (3) and recently we have published a full metabolic re-annotation of its genome (4). This re-annotation can be used, among other applications, to reconstruct genome-scale metabolic models. These models allow anticipating a given organism's phenotype from its genome sequence. The reconstruction of biochemical networks is, currently, a valid alternative to microorganisms modelling as the output provided by the in silico simulations permits focusing on experiments with promising results. Thus, we propose a new fully compartmentalised genome-scale metabolic model for K. lactis, the iOD1759 which comprises 1759 metabolic genes. | por |
dc.language.iso | eng | por |
dc.rights | openAccess | por |
dc.title | Towards a genome-scale metabolic model for the Kluyveromyces lactis yeast | por |
dc.type | conferenceAbstract | por |
dc.peerreviewed | yes | por |
sdum.publicationstatus | published | por |
oaire.citationConferenceDate | 21 - 25 Apr. 2013 | por |
sdum.event.type | conference | por |
oaire.citationStartPage | 1 | por |
oaire.citationEndPage | 2 | por |
oaire.citationConferencePlace | The Hague, The Netherlands | por |
oaire.citationTitle | 9th European Congress of Chemical Engineering / 2nd European Congress of Applied Biotechnology | por |
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abstract.pdf | 105,3 kB | Adobe PDF | Ver/Abrir |