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https://hdl.handle.net/1822/24151
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Campo DC | Valor | Idioma |
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dc.contributor.author | Cunha, Cristina | - |
dc.contributor.author | Carvalho, Agostinho | - |
dc.date.accessioned | 2013-05-22T17:12:13Z | - |
dc.date.available | 2013-05-22T17:12:13Z | - |
dc.date.issued | 2012-03 | - |
dc.identifier.issn | 1478-7210 | por |
dc.identifier.uri | https://hdl.handle.net/1822/24151 | - |
dc.description.abstract | Invasive fungal diseases are life-threatening conditions affecting severely immunocompromised patients such as stem-cell transplant recipients. Recent concerns over antifungal prescription and the exceptionally high healthcare costs owing to the chronic course and high mortality rates of fungal diseases have been shifting the attention from universal antifungal prophylaxis to risk stratification and preemptive approaches [1]. This has motivated the search for ‘individual’ risk factors with prognostic value for the identification of patients most vulnerable to fungal diseases. Therefore, genetic screening strategies are expected to be successfully employed in the near future, to predict risk of disease and efficacy of antifungal therapies. | por |
dc.description.sponsorship | This work was supported by the Specific Targeted Research Project (ALLFUN; FP7−HEALTH−2009 contract number 260338) and the Italian Cystic Fibrosis Research Foundation (Research Project number FFC#21/2010) with the contribution of Francesca Guadagnin, Coca Cola® Light Tribute to Fashion and Delegazione FFC di Belluno. Cristina Cunha and Agostinho Carvalho were financially supported by fellowships from Fundação para a Ciência e Tecnologia, Portugal (contracts SFRH/BD/65962/2009 and SFRH/BPD/46292/2008, respectively). | por |
dc.language.iso | eng | por |
dc.publisher | Expert Reviews | por |
dc.relation | info:eu-repo/grantAgreement/EC/FP7/260338 | - |
dc.rights | restrictedAccess | por |
dc.subject | Fungal disease | por |
dc.subject | GWAS | por |
dc.subject | Human genetics | por |
dc.subject | Immunity | por |
dc.subject | Polymorphism | por |
dc.subject | Transplantation | por |
dc.title | Host genetics and invasive fungal diseases : towards improved diagnosis and therapy? | por |
dc.type | journalEditorial | por |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | http://www.expert-reviews.com/doi/pdfplus/10.1586/eri.12.3 | por |
sdum.publicationstatus | published | por |
oaire.citationStartPage | 257 | por |
oaire.citationEndPage | 259 | por |
oaire.citationIssue | 3 | por |
oaire.citationTitle | Expert Review of Anti-infective Therapy | por |
oaire.citationVolume | 10 | por |
dc.identifier.doi | 10.1586/ERI.12.3 | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Expert Review of Anti-infective Therapy | por |
Aparece nas coleções: | ICVS - Artigos em revistas internacionais / Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Cunha Cristina_Expert Rev. Anti Infect 2012.pdf Acesso restrito! | Author's proof | 2,18 MB | Adobe PDF | Ver/Abrir |