Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/24151

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dc.contributor.authorCunha, Cristina-
dc.contributor.authorCarvalho, Agostinho-
dc.date.accessioned2013-05-22T17:12:13Z-
dc.date.available2013-05-22T17:12:13Z-
dc.date.issued2012-03-
dc.identifier.issn1478-7210por
dc.identifier.urihttp://hdl.handle.net/1822/24151-
dc.description.abstractInvasive fungal diseases are life-threatening conditions affecting severely immunocompromised patients such as stem-cell transplant recipients. Recent concerns over antifungal prescription and the exceptionally high healthcare costs owing to the chronic course and high mortality rates of fungal diseases have been shifting the attention from universal antifungal prophylaxis to risk stratification and preemptive approaches [1]. This has motivated the search for ‘individual’ risk factors with prognostic value for the identification of patients most vulnerable to fungal diseases. Therefore, genetic screening strategies are expected to be successfully employed in the near future, to predict risk of disease and efficacy of antifungal therapies.por
dc.description.sponsorshipThis work was supported by the Specific Targeted Research Project (ALLFUN; FP7−HEALTH−2009 contract number 260338) and the Italian Cystic Fibrosis Research Foundation (Research Project number FFC#21/2010) with the contribution of Francesca Guadagnin, Coca Cola® Light Tribute to Fashion and Delegazione FFC di Belluno. Cristina Cunha and Agostinho Carvalho were financially supported by fellowships from Fundação para a Ciência e Tecnologia, Portugal (contracts SFRH/BD/65962/2009 and SFRH/BPD/46292/2008, respectively).por
dc.language.isoengpor
dc.publisherExpert Reviewspor
dc.relationinfo:eu-repo/grantAgreement/EC/FP7/260338-
dc.rightsrestrictedAccesspor
dc.subjectFungal diseasepor
dc.subjectGWASpor
dc.subjectHuman geneticspor
dc.subjectImmunitypor
dc.subjectPolymorphismpor
dc.subjectTransplantationpor
dc.titleHost genetics and invasive fungal diseases : towards improved diagnosis and therapy?por
dc.typejournalEditorialpor
dc.peerreviewedyespor
dc.relation.publisherversionhttp://www.expert-reviews.com/doi/pdfplus/10.1586/eri.12.3por
sdum.publicationstatuspublishedpor
oaire.citationStartPage257por
oaire.citationEndPage259por
oaire.citationIssue3por
oaire.citationTitleExpert Review of Anti-infective Therapypor
oaire.citationVolume10por
dc.identifier.doi10.1586/ERI.12.3por
dc.subject.wosScience & Technologypor
sdum.journalExpert Review of Anti-infective Therapypor
Appears in Collections:ICVS - Artigos em Revistas Internacionais com Referee

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