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TitleStressed brain, diseased heart : a review on the pathophysiologic mechanisms of neurocardiology
Author(s)Pereira, Vitor H.
Cerqueira, João
Palha, Joana Almeida
Sousa, Nuno
KeywordsCardiovascular diseases
Central nervous system
Chronic stress
Issue dateJun-2013
JournalInternational Journal of Cardiology
CitationPereira VH, et al, Stressed brain, diseased heart: A review on the pathophysiologic mechanisms of neurocardiology, Int J Cardiol (2012), doi:10.1016/j.ijcard.2012.03.165
Abstract(s)Cardiovascular diseases are traditionally related to well known risk factors like dyslipidemia, smoking, diabetes and hypertension. More recently, stress, anxiety and depression have been proposed as risk factors for cardiovascular diseases including heart failure, ischemic disease, hypertension and arrhythmias. Interestingly, this association has been established largely on the basis of epidemiological data, due to insufficient knowledge on the underlying pathophysiologic mechanisms. This review will revisit evidence on the interaction between the cardiovascular and nervous systems, highlighting the perspective on how the central nervous system is involved in the pathogenesis of cardiovascular diseases. Such knowledge is likely to be of relevance for the development of better strategies to treat patients in a holistic perspective.
Publisher version
AccessOpen access
Appears in Collections:ICVS - Artigos em Revistas Internacionais com Referee

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