Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/23815
Título: | Immunotherapy of aspergillosis |
Autor(es): | Carvalho, Agostinho Cunha, Cristina Bistoni, Francesco Romani, Luigina |
Palavras-chave: | Aspergillosis Immunotherapy Single-nucleotide polymorphism |
Data: | Fev-2012 |
Editora: | Wiley-Blackwell |
Revista: | Clinical Microbiology and Infection |
Resumo(s): | Management of invasive aspergillosis in high-risk patients remains challenging. There is an increasing demand for novel therapeutic strategies aimed at enhancing or restoring antifungal immunity in immunocompromised patients. In this regard, modulation of specific innate immune functions and vaccination are promising immunotherapeutic strategies. Recent findings have also provided a compelling rationale for assessment of the contribution of the individual genetic profile to the immunotherapy outcome. Altogether, integration of immunological and genetic data may contribute to the optimization of therapeutic strategies exerting control over immune pathways, ultimately improving the management of fungal infections in high-risk settings. |
Tipo: | Artigo |
Descrição: | We thank C. M. Benedetti for digital art and editing. |
URI: | https://hdl.handle.net/1822/23815 |
DOI: | 10.1111/j.1469-0691.2011.03681.x |
ISSN: | 1198-743X |
Versão da editora: | http://onlinelibrary.wiley.com/doi/10.1111/j.1469-0691.2011.03681.x/pdf |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | ICVS - Artigos em revistas internacionais / Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Carvalho A_Clin Microbiol Infect 2012 pp.pdf | Versão Posprint | 197,62 kB | Adobe PDF | Ver/Abrir |