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https://hdl.handle.net/1822/10220| Título: | Safety issues concerning phage therapy for veterinary applications |
| Autor(es): | Azeredo, Joana Ferreira, Eugénio C. Gannon, B. W. Carvalho, Carla A. O. C. M. Santos, Sílvio Roberto Branco Krylov, V. N. |
| Palavras-chave: | Bacteriophages Safety evaluation Phage‐resistant mutants Bacterial toxins |
| Data: | 2009 |
| Editora: | Universidade do Minho. Departamento de Engenharia Biológica (DEB) |
| Citação: | AZEREDO, Joana [et al.] - Safety issues concerning phage therapy for veterinary applications. In Teixeira, J. A. [et al.], ed. lit. – “Book of abstracts of MicroBiotec09, 3, Vilamoura, Portugal, 2009”. [CD-ROM]. 1st ed. Braga : Departamento de Engenharia Biológica da Universidade do Minho, 2009. ISBN 978-972-97810-6-3. p. 266. |
| Resumo(s): | Phages have been proposed as natural antimicrobial agents to fight bacterial infections in animals. This is supported by several scientific evidences of the efficacy of phage therapy for veterinary applications. However, there are important safety issues that should be taken into consideration when developing a phage product for veterinary applications. For example it is of utmost importance to guarantee that phages are non‐temperate and do not encode bacterial toxins. The phage administration strategy and timing should also be adequate in order to reduce the development of phage‐resistant mutants. The present work describes the main strategies used to ensure a safe phage product for veterinary application, based on the results obtained on the scope of the European Project Phagevet‐P (Veterinary Phage Therapies as Alternatives to Antibiotics in Poultry Production FP6‐2003‐Food‐2‐A:007224). |
| Tipo: | Resumo em ata de conferência |
| URI: | https://hdl.handle.net/1822/10220 |
| ISBN: | 978-972-97810-6-3 |
| Acesso: | Acesso aberto |
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