Data | Título | Autor(es) | Tipo | Acesso |
Mai-2011 | Distinct regulation of p53-mediated apoptosis by protein kinase calpha, delta, epsilon and zeta: evidence in yeast for transcription-dependent and -independent p53 apoptotic mechanisms | Coutinho, Isabel; Pereira, Clara; Pereira, Gil, et al. | Artigo | Acesso aberto |
2021 | Mechanism of Antifungal Activity by 5-Aminoimidazole-4-Carbohydrazonamide Derivatives against Candida albicans and Candida krusei | Cerqueira, Fátima; Maia, Marta; Gabriel, Carla, et al. | Artigo | Acesso aberto |
Mai-2011 | Modulation of Bax by Protein Kinase C in yeast | Silva, Rui D.; Manon, Stéphen; Gonçalves, Jorge, et al. | Resumo em ata de conferência | Acesso aberto |
2011 | Modulation of bax mitochondrial insertion and induced cell death in yeast by mammalian protein kinase calpha | Silva, Rui D.; Manon, Stéphen; Gonçalves, Jorge, et al. | Artigo | Acesso aberto |
13-Abr-2021 | A selective p53 activator and anticancer agent to improve colorectal cancer therapy | Ramos, Helena; Soares, Maria I. L.; Silva, Joana, et al. | Artigo | Acesso aberto |
15-Mar-2021 | Semi-synthesis of small molecules of aminocarbazoles: tumor growth inhibition and potential impact on p53 | Long, Solida; Loureiro, Joana B.; Carvalho, Carla, et al. | Artigo | Acesso aberto |
Jan-2020 | SLMP53-1 interacts with wild-type and mutant p53 DNA-binding domain and reactivates multiple hotspot mutations | Gomes, A. S.; Ramos, Helena; Gomes, S., et al. | Artigo | Acesso aberto |
10-Ago-2019 | SLMP53-2 Restores Wild-Type-Like Function to Mutant p53 through Hsp70: Promising Activity in Hepatocellular Carcinoma | Gomes, Sara; Bosco, Bartolomeo; Loureiro, Joana B., et al. | Artigo | Acesso aberto |
1-Abr-2021 | Targeting p53 for melanoma treatment: counteracting tumour proliferation, dissemination and therapeutic resistance | Loureiro, Joana B.; Raimundo, Liliana; Calheiros, Juliana, et al. | Artigo | Acesso aberto |
2018 | The Crystal Structure of the R280K Mutant of Human p53 Explains the Loss of DNA Binding | Gomes, Ana Sara; Trovão, Filipa; Andrade Pinheiro, Benedita, et al. | Artigo | Acesso aberto |
2011 | The importance of humanized yeast to better understand the role of Bcl-2 family in apoptosis : finding of novel therapeutic opportunities | Silva, Rui D.; Manon, Stéphen; Gonçalves, Jorge, et al. | Artigo | Acesso aberto |
Fev-2017 | Uncovering the binding of the anticancer small molecule SLMP53-1 to mutant p53R280K | Gomes, A. S.; Gomes, S.; Soares, Joana, et al. | Resumo em ata de conferência | Acesso aberto |