Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/91859
Registo completo
Campo DC | Valor | Idioma |
---|---|---|
dc.contributor.author | Carvalho, Duarte Nuno | por |
dc.contributor.author | Reis, R. L. | por |
dc.contributor.author | Silva, Tiago H. | por |
dc.date.accessioned | 2024-06-17T14:30:30Z | - |
dc.date.issued | 2021-08 | - |
dc.date.submitted | 2021-08 | - |
dc.identifier.citation | Carvalho D. N., Reis R. L., Silva T. H. Marine origin materials on biomaterials and advanced therapies to cartilage tissue engineering and regenerative medicine, Biomaterials science, pp. 1-19, doi:10.1039/D1BM00809A, 2021 | por |
dc.identifier.issn | 2047-4849 | por |
dc.identifier.uri | https://hdl.handle.net/1822/91859 | - |
dc.description.abstract | The body's self-repair capacity is limited, including injuries on articular cartilage zones. Over the past few decades, tissue engineering and regenerative medicine (TERM) have focused the studies on the development of natural biomaterials for clinical applications aiming to overcome this self-therapeutic bottleneck. This review focus on the development of these biomaterials using compounds and materials from marine sources, able to be produced in a sustainable way, as an alternative to mammal sources (e.g., collagens) and benefiting from their biological properties, such as biocompatibility, low antigenicity, biodegradability, among others. The structure and composition of the new biomaterials require mimicking the native extracellular matrix (ECM) of articular cartilage tissue. To design an ideal temporary tissue-scaffold, it needs to provide a suitable environment for cell growth (cell attachment, proliferation, and differentiation), towards the regeneration of the damaged tissues. Overall, the purpose of this review is to summarize, various marine sources to be used on the development of different tissue-scaffolds with the capability to sustain cells envisaging cartilage tissue engineering, analysing the systems displaying more promising performance, while pointing current limitations and steps to be given in the near future. | por |
dc.description.sponsorship | The authors thank the Portuguese Foundation for Science and Technology (FCT) for PhD fellowship (Carvalho, D. N.) under the scope of doctoral program Tissue Engineering, Regenerative Medicine and Stem Cells [ref. PD/BD/143044/2018], by ERDF under the scope of Program INTERREG Espana-Portugal 2014-2020 through project 0245_IBEROS_1_E, under the scope of Atlantic Area Program through project BlueHuman [EAPA_151/2016] and COMPETE2020/PT2020 through project SharTech [Ref. 028615]. | por |
dc.language.iso | eng | por |
dc.publisher | ROYAL SOC CHEMISTRY | por |
dc.relation | [ref. PD/BD/143044/2018] | por |
dc.rights | closedAccess | por |
dc.subject | Articular cartilage | por |
dc.subject | Biomedical engineering | por |
dc.subject | Hydrogels | por |
dc.subject | Injectable biomaterials | por |
dc.subject | Marine biomaterials | por |
dc.subject | Marine biopolymers | por |
dc.subject | Tissue-scaffolds | por |
dc.title | Marine origin materials on biomaterials and advanced therapies to cartilage tissue engineering and regenerative medicine | por |
dc.type | article | - |
dc.peerreviewed | no | por |
dc.relation.publisherversion | https://pubs.rsc.org/en/Content/ArticleLanding/2021/BM/D1BM00809A | por |
dc.comments | http://3bs.uminho.pt/node/20557 | por |
oaire.citationStartPage | 6718 | por |
oaire.citationEndPage | 6736 | por |
oaire.citationIssue | 20 | por |
oaire.citationVolume | 9 | por |
dc.date.updated | 2024-06-07T13:29:45Z | - |
dc.identifier.doi | 10.1039/D1BM00809A | por |
dc.date.embargo | 10000-01-01 | - |
dc.identifier.pmid | 34494053 | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Biomaterials Science | por |
Aparece nas coleções: | 3B’s - Artigos em revistas/Papers in scientific journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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20557-review.pdf Acesso restrito! | 2,7 MB | Adobe PDF | Ver/Abrir |