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Biodegradable nanoparticles for the treatment of epilepsy: from current advances to future challenges

Summary Epilepsy is the second most prevalent neurological disease worldwide. It is mainly characterized by an electrical abnormal activity in different brain regions. The massive entrance of Ca2+ into neurons is the main neurotoxic process that lead to cell death and finally to neurodegeneration. Although there are a huge number of antiseizure medications, there are many patients who do not respond to t...

Recent advances in the valorization of algae polysaccharides for food and nutraceutical applications: a review on the role of green processing technologies

Recently, there are two main movements gaining public attention: a ``green revolution'' focused on the use of sustainable processes and the increasing concerns with health-promoting diets and the recognition of the gut microbiota and its effects on the treatment and prevention of several diseases. Microalgae and macroalgae arise as an interesting alternative to obtain these nutraceutical compounds in a s...

Innovative swine blood hydrolysates as promising ingredients for European seabass diets: Impact on growth performance and resistance to Tenacibaculum maritimum infection

Hydrolysates from high-protein coproducts are rich in bioactive peptides (small amino acid chains with properties beyond their nutritional value). When included in aquafeeds, they may promote fish robustness while increasing animal blood value and minimizing waste, contributing to a circular economy. This work assessed how innovatively produced blood hydrolysates (BH) included in plant-based diets for Eu...

Development of a realistic in vitro digestion model (RGM) coupled UV-VIS-SWNIR fibre optics spectroscopy

Background: The development of realistic gastric models unlocked the possibility of studying important digestion phenomena occurring during the digestion of food (e.g., retropulsion). Understanding the dynamics of food digestion in real-time, without sample manipulation, is still a challenge, but brings a huge potential in providing important insights regarding the dynamic process of food digestion (...

In vitro digestion and storage stability of riboflavin-loaded WPI nanostructures towards foods fortification

The consumption of fortified foods incorporating bioactive compounds as a way to promote a healthier lifestyle has gain particular interest in research community and food industry. However, due to their chemical instabilities, bioactive compounds bioavailability can be compromised during post-processing, storage, and digestion. Their encapsulation/association in nanostructures offers a good strategy ...

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