Background Patch repair of congenital diaphragmatic hernia (CDH) using Gore-Tex® is associated with infection, adhesions, hernia recurrence, long-term musculoskeletal sequels and poor tissue regeneration. To overcome these limitations, the performance of&#x...

[Excerpt] Introduction: 3D in vitro skin models allow studying molecular pathways that otherwise are only possible to explore using animal models. The incorporation of immune cells, such as macrophages, has been implemented ...

[Excerpt] Introduction: Collagen I (Col I) is the gold standard material to generate many in vitro tissue models, including organotypic skin. Col I remodeling by fibroblasts incorporated in the dermal part of the model ...

[Excerpt] Introduction: Current radio- and chemotherapies are not efficient and many tumors remain resistant to conventional cancer treatments. Specific properties and signaling molecules from tumor microenvironment (TME) have been explor...