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https://hdl.handle.net/1822/77870
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Campo DC | Valor | Idioma |
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dc.contributor.author | Decante, Guy | por |
dc.contributor.author | Oliveira, J. M. | por |
dc.contributor.author | Reis, R. L. | por |
dc.contributor.author | Correia, Joana Silva | por |
dc.date.accessioned | 2022-05-24T14:08:36Z | - |
dc.date.issued | 2021-09 | - |
dc.date.submitted | 2021-03 | - |
dc.identifier.citation | Decante G., Oliveira J. M., Reis R. L., Silva-Correia J. Injectable Polymeric Systems Based on Polysaccharides for Therapy, Polysaccharides of Microbial Origin, doi:10.1007/978-3-030-35734-4_55-1, 2021 | por |
dc.identifier.isbn | 978-3-030-35734-4 | por |
dc.identifier.uri | https://hdl.handle.net/1822/77870 | - |
dc.description.abstract | Microbial polysaccharides are inexpensive natural polymers synthesized by various microorganisms such as bacteria, fungi, and microalgae. They have been generally used in the food industry as emulsifier, gelling agents, and thickeners. Nowadays, their favourable biological properties, similarity to native ECM, and wide range of molecular weights, and functional groups have sparked the interest of researchers for their use as injectable scaffolds used in drug delivery, tissue engineering and regenerative medicine. Notable applications of microbial polysaccharides are vaccine preparations and intra-articular injections of hydrogels in osteoarthritis therapy. These systems provide minimally invasive routes of implantation in vivo to locally deliver drugs, cells, and other therapeutics in a controlled manner. They may also provide a stable environment to support cell differentiation and migration to enhance tissue regeneration. The various uses of microbial polysaccharides and their derivatives as injectable scaffolds used in therapy are reviewed herein. | por |
dc.description.sponsorship | The authors acknowledge the financial support provided through the projects B-FABULUS (PTDC/BBB-ECT/2690/2014) and Fun4TE (PTDC/EMD-EMD/31367/2017), financed by the Portuguese Foundation for Science and Technology (FCT) and co-financed by European Regional Development Fund (FEDER) and Operational Programme for Competitiveness and Internationalisation (POCI). This work has been co-funded through the project 3BioMeD (FCT/4773/4/5/2017/S). G. Decante acknowledges for his research fellowship (BI_ PTDC/BBB-ECT/2690/2014_2020_01) attributed under B-FABULUS project. The FCT distinction attributed to J. Silva-Correia Oliveira (IF/00115/2015) under the Investigator FCT program is also greatly acknowledged. | por |
dc.language.iso | eng | por |
dc.publisher | Springer | por |
dc.relation | info:eu-repo/grantAgreement/FCT/3599-PPCDT/PTDC%2FBBB-ECT%2F2690%2F2014/PT | por |
dc.relation | info:eu-repo/grantAgreement/FCT/9471 - RIDTI/PTDC%2FEMD-EMD%2F31367%2F2017/PT | por |
dc.relation | info:eu-repo/grantAgreement/FCT/3599-PPCDT/PTDC%2FBBB-ECT%2F2690%2F2014/PT | por |
dc.relation | info:eu-repo/grantAgreement/FCT/Investigador FCT/IF%2F00115%2F2015%2FCP1294%2FCT0005/PT | por |
dc.rights | restrictedAccess | por |
dc.subject | Bacteria | por |
dc.subject | Drug delivery | por |
dc.subject | Hydrogels | por |
dc.subject | Polysaccharides | por |
dc.subject | Tissue engineering | por |
dc.title | Injectable polymeric systems based on polysaccharides for therapy | por |
dc.type | bookPart | por |
dc.peerreviewed | yes | - |
dc.relation.publisherversion | https://link.springer.com/referenceworkentry/10.1007%2F978-3-030-35734-4_55-1 | por |
dc.comments | http://3bs.uminho.pt/node/20504 | por |
oaire.citationStartPage | 1 | por |
oaire.citationEndPage | 18 | por |
dc.date.updated | 2022-05-18T10:22:45Z | - |
dc.identifier.doi | 10.1007/978-3-030-35734-4_55-1 | por |
dc.date.embargo | 10000-01-01 | - |
sdum.bookTitle | Polysaccharides of microbial origin | por |
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