Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/76240
Título: | Exosome-mediated MEK1 silencing is a promising approach against triple negative breast cancer regression |
Autor(es): | Ferreira, Débora Cátia S. Pereira Costa, Marta Afonso, Julieta Longatto, Adhemar Baltazar, Fátima Kalluri, Raghu Moreira, João N. Rodrigues, L. R. |
Data: | 28-Jan-2022 |
Citação: | Ferreira, Débora; Cátia S. Pereira; Costa, Marta; Afonso, Julieta; Longatto-Filho, Adhemar; Baltazar, Fátima; Kalluri, Raghu; Moreira, João N.; Rodrigues, Lígia R., Exosome-mediated MEK1 silencing is a promising approach against triple negative breast cancer regression. XIV Spanish-Portuguese Conference on Controlled Drug Delivery. Tenerife, Spain, Jan 26-28, 43-44, 2022. |
Resumo(s): | [Excerpt] Introduction: Breast cancer is a major public health problem worldwide being the most diagnosed cancer in women [1] . Triple negative breast cancer (TNBC) represents 10-20% of all breast cancers and is characterized by the absence of hormone receptors (progesterone and estrogen) and lack of expression of epidermal growth factor receptor 2. Furthermore, it is also described to have poor prognosis due to its propensity to metastasize to visceral organs early in the clinical course [2–4] . In accordance with the lack of recurrently altered targets at the genomic level, there is a shortage of approved targeted agents for TNBC, remaining cytotoxic chemotherapy the mainstay of treatment. [...] |
Tipo: | Resumo em ata de conferência |
URI: | https://hdl.handle.net/1822/76240 |
Versão da editora: | https://www.splc-crs.org/meeting-2022/ |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CBMA - Resumos em livros de atas/Abstracts in proceedings |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_55319_1.pdf | 146,76 kB | Adobe PDF | Ver/Abrir |