Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/74709
Registo completo
Campo DC | Valor | Idioma |
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dc.contributor.author | Maia, F. Raquel | por |
dc.contributor.author | Bastos, Ana Raquel Fernandes | por |
dc.contributor.author | Oliveira, J. M. | por |
dc.contributor.author | Correlo, V. M. | por |
dc.contributor.author | Reis, R. L. | por |
dc.date.accessioned | 2021-11-16T09:27:44Z | - |
dc.date.available | 2024-03-01T07:00:43Z | - |
dc.date.issued | 2022-02 | - |
dc.date.submitted | 2021-11 | - |
dc.identifier.citation | Maia F. R., Bastos A. R., Oliveira J. M., Correlo V.M., Reis R. L. Recent approaches towards bone tissue engineering, Bone, doi:10.1016/j.bone.2021.116256, 2021 | por |
dc.identifier.issn | 8756-3282 | por |
dc.identifier.uri | https://hdl.handle.net/1822/74709 | - |
dc.description.abstract | Bone tissue engineering approaches have evolved towards addressing the challenges of tissue mimetic requirements over the years. Different strategies have been combining scaffolds, cells, and biologically active cues using a wide range of fabrication techniques, envisioning the mimicry of bone tissue. On the one hand, biomimetic scaffold-based strategies have been pursuing different biomaterials to produce scaffolds, combining with diverse and innovative fabrication strategies to mimic bone tissue better, surpassing bone grafts. On the other hand, biomimetic scaffold-free approaches mainly foresee replicating endochondral ossification, replacing hyaline cartilage with new bone. Finally, since bone tissue is highly vascularized, new strategies focused on developing pre-vascularized scaffolds or pre-vascularized cellular aggregates have been a motif of study. The recent biomimetic scaffold-based and scaffold-free approaches in bone tissue engineering, focusing on materials and fabrication methods used, are overviewed herein. The biomimetic vascularized approaches are also discussed, namely the development of pre-vascularized scaffolds and pre-vascularized cellular aggregates. | por |
dc.description.sponsorship | F.R. Maia acknowledges the funds provided by the Research and Innovation Staff Exchanges (RISE) action (H2020 Marie Skłodowska-Curie actions) for funds obtained through the BAMOS project (H2020-MSCA-RISE-2016-734156), the R&D Project KOAT PTDC/BTMMAT/29760/2017 (POCI-01-0145-FEDER-029760), financed by the Portuguese Foundation for Science and Technology (FCT) and co-financed by FEDER and POCI, and FCT for her work contract under the Transitional Rule DL 57/2016 (CTTI-57/18-I3BS5). A. R. Bastos thanks the funds provided by FCT under the doctoral program in Tissue Engineering, Regenerative Medicine and Stem Cells (PD/BD/143043/2018). | por |
dc.language.iso | eng | por |
dc.publisher | Elsevier 1 | por |
dc.relation | info:eu-repo/grantAgreement/EC/H2020/734156/EU | por |
dc.relation | info:eu-repo/grantAgreement/FCT/POR_NORTE/PD%2FBD%2F143043%2F2018/PT | por |
dc.rights | openAccess | por |
dc.subject | 3D bioprinting | por |
dc.subject | 3D printing | por |
dc.subject | Bone tissue engineering | por |
dc.subject | Scaffolds | por |
dc.subject | Spheroids | por |
dc.subject | Vascularized strategies | por |
dc.title | Recent approaches towards bone tissue engineering | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | https://doi.org/10.1016/j.bone.2021.116256 | por |
dc.comments | http://3bs.uminho.pt/node/20615 | por |
oaire.citationStartPage | 116256 | por |
oaire.citationEndPage | 116256 | por |
oaire.citationVolume | 154 | por |
dc.date.updated | 2021-11-15T17:48:19Z | - |
dc.identifier.doi | 10.1016/j.bone.2021.116256 | por |
dc.identifier.pmid | 34781047 | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Bone | por |
Aparece nas coleções: | 3B’s - Artigos em revistas/Papers in scientific journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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20615-1-s20-s8756328221004221-main.pdf | 7,11 MB | Adobe PDF | Ver/Abrir |