Investigation of osteoblast response to biodegradable bacterial cellulose scaffolds

Abstract

[Excerpt] Aim of this project is to investigate the ability of bacterial cellulose (BC) and oxidized Bacterial cellulose (OBC) use as a scaffold in tissue engineering. Bacterial cellulose was produced with being provided optimum conditions from Acetobacter xylinus. BC was transformed dialdehyde cellulose (DAC) as biodegradable form by treating with periodate. Oxidation was carried out in aqueous solution at 508C in the dark for 24 hours. The mole-to-mole ratio of sodium metaperiodate to anhydroglucose repeat unit (AGU) of cellulose was 0.5, 1.0 and 1.5. [...]