Please use this identifier to cite or link to this item: https://hdl.handle.net/1822/58062

TitleLarge-scale genomic analysis shows association between homoplastic genetic variation in Mycobacterium tuberculosis genes and meningeal or pulmonary tuberculosis
Author(s)Ruesen, Carolien
Chaidir, Lidya
van Laarhoven, Arjan
Dian, Sofiati
Ganiem, Ahmad Rizal
Guimarães, Hanna Nebenzahl
Huynen, Martijn A.
Alisjahbana, Bachti
Dutilh, Bas E.
van Crevel, Reinout
KeywordsComputational Biology
Genomics
Humans
Indonesia
Mycobacterium tuberculosis
Phenotype
Phylogeny
Polymorphism, Single Nucleotide
Tuberculosis, Meningeal
Tuberculosis, Pulmonary
Genes, Bacterial
Genetic Variation
Genome, Bacterial
Pulmonary tuberculosis
Tuberculous meningitis
Whole genome sequencing
Homoplasy
Issue date2018
PublisherSpringer Nature
JournalBMC Genomics
CitationRuesen, C., Chaidir, L., van Laarhoven, A., Dian, S., Ganiem, A. R., et. al. (2018). Large-scale genomic analysis shows association between homoplastic genetic variation in Mycobacterium tuberculosis genes and meningeal or pulmonary tuberculosis. BMC genomics, 19(1), 122
Abstract(s)Meningitis is the most severe manifestation of tuberculosis. It is largely unknown why some people develop pulmonary TB (PTB) and others TB meningitis (TBM); we examined if the genetic background of infecting M. tuberculosis strains may be relevant.
TypeArticle
URIhttps://hdl.handle.net/1822/58062
DOI10.1186/s12864-018-4498-z
ISSN1471-2164
e-ISSN1471-2164
Publisher versionhttps://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-018-4498-z
Peer-Reviewedyes
AccessOpen access
Appears in Collections:ICVS - Artigos em revistas internacionais / Papers in international journals

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