Utilize este identificador para referenciar este registo: https://hdl.handle.net/1822/58062

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dc.contributor.authorRuesen, Carolienpor
dc.contributor.authorChaidir, Lidyapor
dc.contributor.authorvan Laarhoven, Arjanpor
dc.contributor.authorDian, Sofiatipor
dc.contributor.authorGaniem, Ahmad Rizalpor
dc.contributor.authorGuimarães, Hanna Nebenzahlpor
dc.contributor.authorHuynen, Martijn A.por
dc.contributor.authorAlisjahbana, Bachtipor
dc.contributor.authorDutilh, Bas E.por
dc.contributor.authorvan Crevel, Reinoutpor
dc.date.accessioned2019-01-11T12:39:13Z-
dc.date.available2019-01-11T12:39:13Z-
dc.date.issued2018-
dc.identifier.citationRuesen, C., Chaidir, L., van Laarhoven, A., Dian, S., Ganiem, A. R., et. al. (2018). Large-scale genomic analysis shows association between homoplastic genetic variation in Mycobacterium tuberculosis genes and meningeal or pulmonary tuberculosis. BMC genomics, 19(1), 122por
dc.identifier.issn1471-2164por
dc.identifier.urihttps://hdl.handle.net/1822/58062-
dc.description.abstractMeningitis is the most severe manifestation of tuberculosis. It is largely unknown why some people develop pulmonary TB (PTB) and others TB meningitis (TBM); we examined if the genetic background of infecting M. tuberculosis strains may be relevant.por
dc.description.sponsorshipThis study was supported by the Royal Netherlands Academy of Arts and Sciences (KNAW). [09-PD-14 to RvC]; fellowship from the Netherlands Organization for Health Research and Development (ZonMw) and The Netherlands Foundation for Scientific Research [VIDI grant. 017.106.310 to RvC., and VIDI grant 864.14.004 to BED.]; and Radboud University fellowship [to CR]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. This study was also supported by the TANDEM (Tuberculosis and Diabetes Mellitus) Grant of the ECFP7 (European Union’s Seventh Framework Programme) under Grant Agreement no. 305279por
dc.language.isoengpor
dc.publisherSpringer Naturepor
dc.rightsopenAccesspor
dc.subjectComputational Biologypor
dc.subjectGenomicspor
dc.subjectHumanspor
dc.subjectIndonesiapor
dc.subjectMycobacterium tuberculosispor
dc.subjectPhenotypepor
dc.subjectPhylogenypor
dc.subjectPolymorphism, Single Nucleotidepor
dc.subjectTuberculosis, Meningealpor
dc.subjectTuberculosis, Pulmonarypor
dc.subjectGenes, Bacterialpor
dc.subjectGenetic Variationpor
dc.subjectGenome, Bacterialpor
dc.subjectPulmonary tuberculosispor
dc.subjectTuberculous meningitispor
dc.subjectWhole genome sequencingpor
dc.subjectHomoplasypor
dc.titleLarge-scale genomic analysis shows association between homoplastic genetic variation in Mycobacterium tuberculosis genes and meningeal or pulmonary tuberculosispor
dc.typearticlepor
dc.peerreviewedyespor
dc.relation.publisherversionhttps://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-018-4498-zpor
oaire.citationIssue122por
oaire.citationVolume19por
dc.identifier.eissn1471-2164-
dc.identifier.doi10.1186/s12864-018-4498-zpor
dc.identifier.pmid29402222por
dc.subject.fosCiências Médicas::Medicina Básicapor
dc.description.publicationversioninfo:eu-repo/semantics/publishedVersionpor
dc.subject.wosScience & Technologypor
sdum.journalBMC Genomicspor
Aparece nas coleções:ICVS - Artigos em revistas internacionais / Papers in international journals

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