Functionalised collagen-MnO2 fibres inhibit oxidative-induced apoptosis in degenerated IVD

Utilize este identificador para referenciar este registo: https://hdl.handle.net/1822/42503

Registo completo

Campo DC	Valor	Idioma
dc.contributor.author	Pereira, Diana Ribeiro	por
dc.contributor.author	Tapeinos, C.	por
dc.contributor.author	Oliveira, J. M.	por
dc.contributor.author	Reis, R. L.	por
dc.contributor.author	Pandit, A.	por
dc.date.accessioned	2016-09-08T13:42:04Z	-
dc.date.available	2016-09-08T13:42:04Z	-
dc.date.issued	2016-07	-
dc.identifier.citation	Pereira D. R., Tapeinos C., Oliveira J. M., Reis R. L., Pandit A. Functionalised collagen-MnO2 fibres inhibit oxidative-induced apoptosis in degenerated IVD, European Cells & Materials, Vol. 31, Issue 1, pp. P50, 14732262, 2016	-
dc.identifier.issn	14732262	-
dc.identifier.uri	https://hdl.handle.net/1822/42503	-
dc.description.abstract	Intervertebral disc cell apoptosis has been reported as the major factor responsible in promoting disc degeneration. In this study we hypothesize that collagen fibres with manganese dioxide (MnO2) nanoparticles (NPs) can increase oxygen levels by scavenging ROS species and converting it into byproducts. The specific objective of this study is to fabricate collagen fibres incorporating NPs (Fig. 1), with controlled degradability that are able to scavenge ROS species and generate O2 while inhibiting annulus fibrosus (AF) cell apoptosis under inflamed conditions.	por
dc.description.sponsorship	Science Foundation Ireland (SFI), the European Regional Development Fund (13/RC/2073)	por
dc.description.sponsorship	Portuguese Foundation for Science and Technology (SFRH/BD/81356/2011)	por
dc.language.iso	eng	por
dc.publisher	AO Foundation	por
dc.relation	info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F81356%2F2011/PT	por
dc.rights	openAccess	por
dc.subject	Collagen	por
dc.subject	IL1b	por
dc.subject	IVD	por
dc.subject	Manganese dioxide	por
dc.subject	Nanoparticles	por
dc.subject	ROS	por
dc.subject	Scavenging effect	por
dc.title	Functionalised collagen-MnO2 fibres inhibit oxidative-induced apoptosis in degenerated IVD	por
dc.type	conferenceAbstract	-
dc.peerreviewed	yes	por
dc.relation.publisherversion	http://www.ecmjournal.org/journal/supplements/vol031supp01/vol031supp01_P.htm	por
dc.comments	http://3bs.uminho.pt/node/18776	por
sdum.publicationstatus	info:eu-repo/semantics/publishedVersion	por
oaire.citationConferenceDate	28 June - 01 July 2016	por
sdum.event.type	conference	por
oaire.citationStartPage	P50	por
oaire.citationEndPage	P50	por
oaire.citationIssue	1	-
oaire.citationConferencePlace	Uppsala, Sweden	por
oaire.citationTitle	TERMIS-EU 2016 Conference "Towards Future Regenerative Therapies"	por
oaire.citationVolume	31	-
dc.date.updated	2016-09-05T16:04:57Z	-
Aparece nas coleções:	3B’s - Resumos em livros de atas de conferências - indexados no ISI Web of Science

Ficheiros deste registo:

Ficheiro	Descrição	Tamanho	Formato
18776-Diana_Pereira.pdf		1,05 MB	Adobe PDF	Ver/Abrir

Ver registo simples Sugerir correção Estatísticas