Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/38384
Registo completo
Campo DC | Valor | Idioma |
---|---|---|
dc.contributor.author | Duarte, Ana Rita C. | por |
dc.contributor.author | Mano, J. F. | por |
dc.contributor.author | Reis, R. L. | por |
dc.date.accessioned | 2015-11-24T12:29:49Z | - |
dc.date.available | 2015-11-24T12:29:49Z | - |
dc.date.issued | 2015-10 | - |
dc.date.submitted | 2015-11 | - |
dc.identifier.citation | Duarte A. R. C., Mano J. F., Reis R. L. Polymer Processing Using Supercritical Fluid Based Technologies for Drug Delivery and Tissue Engineering Applications, Supercritical Fluid Nanotechnology, pp. 273-288, 978-981-2613-40.8, 2015 | - |
dc.identifier.isbn | 978-981-4613-40-8 | por |
dc.identifier.isbn | 978-981-4613-41-5 | por |
dc.identifier.uri | https://hdl.handle.net/1822/38384 | - |
dc.description.abstract | From the use of botanical plants in early human civilizations through synthetic chemistry and biotechnology, drug research has always passionate scientists creating exciting challenges to a large number of researchers from different fields, thus, promoting a collaborative effort between polymer scientists, pharmacologists, engineers, chemists and medical researchers. Worldwide, there is an increasing concern on health care that creates a major opportunity for development of new pharmaceutical formulations. Ageing populations worried about the quality of life in the older years are actively seeking for new, more effective and patient compliant drug delivery devices. This has been the driving force for the continuous growth of the research made on delivery devices, which has become a powerful technique in health care. It has been recognized for long that simple pills or injections may not be the suitable methods of administration of a certain active compound. These medications present several problems and/or limitations, like poor drug bioavailability and systemic toxicity, derived essentially from pharmacokinetic and other carrier limitations and low solubility of the drugs in water. Therefore and to overcome these drawbacks, clinicians recommend frequent drug dosing, at high concentrations, in order to overcome poor drug bioavailability but causing a potential risk of systemic toxicity. Polymer science has open new strategies for drug delivery systems. This Chapter overviews of possible strategies involving polymer modification and processing for controlled drug delivery and drug delivery in tissue engineering. | por |
dc.description.sponsorship | European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement number REGPOT-CT2012-316331-POLARIS and from the project “Novel smart and biomimetic materials for innovative regenerative medicine approaches” RL1 -ABMR-NORTE-01-0124-FEDER-000016 cofinanced by North Portugal Regional Operational Programme (ON.2 –O Novo Norte), under the National Strategic Reference Framework (NSRF), through the European Regional Development Fund (ERDF). | por |
dc.language.iso | eng | por |
dc.publisher | Pan Stanford Publishing | por |
dc.relation | info:eu-repo/grantAgreement/EC/FP7/316331/EU | por |
dc.rights | openAccess | por |
dc.subject | Drug delivery | por |
dc.subject | Impregnation | por |
dc.subject | Pharmaceutics | por |
dc.subject | Supercritical fluids | por |
dc.title | Polymer processing using supercritical fluid based technologies for drug delivery and tissue engineering applications | por |
dc.type | bookPart | por |
dc.peerreviewed | yes | - |
dc.relation.publisherversion | http://www.panstanford.com/books/9789814613408.html | por |
dc.comments | http://www.3bs.uminho.pt/node/18599 | por |
sdum.publicationstatus | published | - |
oaire.citationStartPage | 273 | por |
oaire.citationEndPage | 288 | por |
oaire.citationTitle | Supercritical Fluid Nanotechnology: Advances and Applications in Composites and Hybrid Nanomaterials | por |
dc.date.updated | 2015-11-09T16:12:08Z | - |
dc.identifier.doi | 10.1201/b19242-14 | - |
dc.subject.fos | Ciências Médicas::Biotecnologia Médica | por |
sdum.bookTitle | Supercritical Fluid Nanotechnology: Advances and Applications in Composites and Hybrid Nanomaterials | por |
Aparece nas coleções: |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
---|---|---|---|---|
18599-Chapter 12_ARita.pdf | 349,33 kB | Adobe PDF | Ver/Abrir |