Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/33044
Título: | A software tool for network topology analysis under a Metabolic Engineering perspective |
Autor(es): | Pinto, José P. Rocha, I. Rocha, Miguel |
Palavras-chave: | Metabolic network Network topology analysis Metabolic engineering Graph algorithms Open-source software Metabolic networks |
Data: | 2010 |
Editora: | ACM |
Citação: | José Pedro Pinto; Rocha, I.; Rocha, Miguel, A software tool for network topology analysis under a metabolic engineering perspective. BCB 2010 - Proceedings of the ACM Conference on Bioinformatics and Computational Biology. New York, USA, 2010, 569-578, 2010. |
Resumo(s): | In this work, we present a software application that runs as a plug-in over the OptFlux Metabolic Engineering platform allowing the topological analysis of metabolic networks. The major aim of this tool is to allow the interconnection between phenotype simulation tasks (using algorithms such as Flux Balance Analysis) and topological analysis of the same networks. The provided methods include node degree and degree distributions, shortest path analysis, clustering coefficients and several node rankers (betweenness and closeness centrality, hubs and authorities, etc). Also, it allows the creation of sub-networks through severalfilters, including some based on the results of phenotype simulation. |
Tipo: | Artigo em ata de conferência |
URI: | https://hdl.handle.net/1822/33044 |
ISBN: | 9781450304382 |
DOI: | 10.1145/1854776.1854884 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CEB - Artigos em Livros de Atas / Papers in Proceedings |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_10589_1.pdf | 4,69 MB | Adobe PDF | Ver/Abrir |