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https://hdl.handle.net/1822/26963
Título: | Magnetic-responsive hydrogels for cartilage tissue engineering |
Autor(es): | Popa, Elena Geta Rodrigues, Márcia T. Santo, Vítor E. Gonçalves, A. I. Reis, R. L. Gomes, Manuela E. |
Palavras-chave: | Cartilage TE Hydrogels Magnetic nanoparticles Stem cells |
Data: | Set-2013 |
Editora: | John Wiley and Sons |
Citação: | Popa E. G., Rodrigues M. T., Santo V. E., Gonçalves A. I., Reis R. L., Gomes M. E. Magnetic-responsive hydrogels for cartilage tissue engineering, Journal of Tissue Engineering and Regenerative Medicine, Vol. 7, Issue s1, pp. 22-22, doi: 10.1002/term.1822, 2013 |
Resumo(s): | The use of magnetic nanoparticles (MNPs) has been explored as an alternative approach to overcome current limitations of regenerative medicine strategies. Cell engineering approaches where MNPs are incorporated within three-dimensional constructs, such as scaffolds or hydrogels may constitute a novel and attractive approach towards the development of a magnetically-responsive system. These systems would enable remote controlled actions over tissue engineered constructs in vitro and in vivo. Moreover, growing evidence suggests that the application of a magnetic field may enhance biological performance over commonly used static culture conditions providing stimulation for cell proliferation, migration and differentiation. In this work we analyze the role of magnetic stimulation on the behavior of human adipose derived stem cells (hASCs) laden in k-carrageenan hydrogels aiming at cartilage tissue engineering approaches. Thermo-responsive natural-based κ-carrageenan hydrogels were used as 3D templates since previous studies(1) report the adequate environment provided by these materials to support the viability and chondrogenic differentiation of several types of cells. |
Tipo: | Resumo em ata de conferência |
Descrição: | Publicado em "Journal of Tissue Engineering and Regenerative Medicine", vol. 7, supp. 1 (2013) |
URI: | https://hdl.handle.net/1822/26963 |
Versão da editora: | http://onlinelibrary.wiley.com/doi/10.1002/term.1822/abstract |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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17676-Magnetic-responsive hydrogels for cartilage TE.pdf | 48,71 kB | Adobe PDF | Ver/Abrir |