Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/25591
Título: | Alternative methodology for chitin/hydroxyapatite composites using ionic liquids and supercritical fluid technology |
Autor(es): | Silva, Simone Santos Duarte, Ana Rita C. Oliveira, Joaquim M. Mano, J. F. Reis, R. L. |
Palavras-chave: | Chitin Hydroxyapatite Ionic liquids Supercritical fluid technology scaffold pores sizing Composites salt leaching controlled pore sizes |
Data: | Ago-2013 |
Editora: | SAGE |
Revista: | Journal of Bioactive and Compatible Polymers |
Resumo(s): | An alternative, green method was used to develop chitin-based biocomposite (ChHA) materials by an integrated strategy using ionic liquids, supercritical fluid drying, and salt leaching. ChHA matrices were produced by dissolving chitin in 1-butyl-methylimidazolium acetate along with salt and/or hydroxyapatite particles and then subsequent drying. The ChHA composite formed had a heterogeneous porous microstructure with 65%–85% porosity and pore sizes in the range of 100–300 µm. The hydroxyapatite was found to be well distributed within the composite structures and had a positive effect in the viability and proliferation of osteoblast-like cells, in vitro. Our findings indicate that these ChHA matrices have potential applications in bone tissue engineering. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/25591 |
DOI: | 10.1177/0883911513501595 |
ISSN: | 0883–9115 |
Versão da editora: | http://jbc.sagepub.com/content/28/5/481 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | 3B’s - Artigos em revistas/Papers in scientific journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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17661-Journal of Bioactive and compatible polymers_ Silva et al 2013.pdf | 1,32 MB | Adobe PDF | Ver/Abrir |