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TitleBioactive silicate nanoplatelets for osteogenic differentiation of human mesenchymal stem cells
Author(s)Gaharwar, Akhilesh K.
Mihaila, Silvia M.
Swami, A.
Patel, A.
Sant, A.
Reis, R. L.
Marques, A. P.
Gomes, Manuela E.
Khademhosseini, Ali
KeywordsOsteogenic differentiation
Silicate nanoplatelets
Stem cells
synthetic clay
laponite nanoparticles
human mesenchymal stem cells
tissue engineering
Issue dateMay-2013
PublisherWiley-VCH Verlag
JournalAdvanced Materials
Abstract(s)Novel silicate nanoplatelets that induce osteogenic differentiation of human mesenchymal stem cells (hMSCs) in the absence of any osteoinductive factor are reported. The presence of the silicate triggers a set of events that follows the temporal pattern of osteogenic differentiation. These findings underscore the potential applications of these silicate nanoplatelets in designing bioactive scaffolds for musculoskeletal tissue engineering.
ISSN1521-4095 (on-line)
Publisher version
AccessRestricted access (UMinho)
Appears in Collections:3B’s - Artigos em revistas/Papers in scientific journals

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