Please use this identifier to cite or link to this item: https://hdl.handle.net/1822/14013

TitleChitosan derivatives obtained by chemical modifications for biomedical and environmental applications
Author(s)Alves, N. M.
Mano, J. F.
KeywordsChitosan
Chitosan derivatives
Biomedical applications
Biomaterials
Polysaccharides
Issue date2008
PublisherElsevier
JournalInternational Journal of Biological Macromolecules
Abstract(s)Chitosan is a natural based polymer, obtained by alkaline deacetylation of chitin, which presents excellent biological properties such as biodegradability and immunological, antibacterial and wound-healing activity. Recently, there has been a growing interest in the chemical modification of chitosan in order to improve its solubility and widen its applications. The main chemical modifications of chitosan that have been proposed in the literature are reviewed in this paper. Moreover, these chemical modifications lead to a wide range of derivatives with a broad range of applications. Recent and relevant examples of the distinct applications, with particular emphasis on tissue engineering, drug delivery and environmental applications, are presented.
TypeArticle
URIhttps://hdl.handle.net/1822/14013
DOI10.1016/j.ijbiomac.2008.09.007
ISSN0141-8130
Peer-Reviewedyes
AccessOpen access
Appears in Collections:3B’s - Artigos em revistas/Papers in scientific journals

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