Utilize este identificador para referenciar este registo: https://hdl.handle.net/1822/91466

TítuloDevelopment and optimization of a SPME-GC-FID method for ethanol detection
Autor(es)Costa, Nuna G.
Freitas, David Silva
Barros, Aline Magalhães
Silva, Carla
Antunes, Joana C.
Rocha, Ana M.
Palavras-chaveArtificial sweat
Ethanol
Flame ionization
Gas chromatography
SPME
Data24-Jan-2024
EditoraMDPI
RevistaProcesses
CitaçãoCosta, Nuna G.; Freitas, David; Barros, Aline; Silva, Carla; Antunes, Joana C.; Rocha, Ana M., Development and optimization of a SPME-GC-FID method for ethanol detection. Processes, 12(2), 247, 2024
Resumo(s)A solid-phase microextraction (SPME) injection gas chromatography was validated with the flame ionization detection method (GC-FID) using a capillary column to detect ethanol. The method was used to determine ethanol in fluids with biomedical, clinical, and forensic importance, including water, phosphate-buffered saline (PBS), and artificial sweat. The strategy produced good peak resolution and showed a linear correlation between the concentration and peak areas for ethanol in all matrices. The inter- and intra-day precisions of the method were below 15.5% and 6.5%, respectively, varying according to the matrix. The method achieved detection limits below 1.3 mg/L, varying according to the matrix. Lower limits were obtained for the aqueous solution (0.22 mg/L), followed by the PBS solution (0.96 mg/L), and finally, the sweat solution (1.29 mg/L). This method is easy to perform and suitable for use in routine clinical biochemistry and forensic laboratories, allowing ethanol detection at lower concentrations using lower temperature and time of extraction, when compared with other studies.
TipoArtigo
URIhttps://hdl.handle.net/1822/91466
DOI10.3390/pr12020247
ISSN2227-9717
Versão da editorahttps://www.mdpi.com/journal/processes
Arbitragem científicayes
AcessoAcesso aberto
Aparece nas coleções:CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

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