Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/87519
Título: | Neural binocular summation and the effect of defocus on the pattern electroretinogram and visual evoked potentials for different pupil sizes |
Autor(es): | Martino, Francesco Amorim-de-Sousa, Ana Fernandes, Paulo Castro-Torres, José Juan González-Méijome, José Manuel |
Palavras-chave: | binocular summation defocus electroretinogram pupil size visual evoked potential |
Data: | Nov-2023 |
Editora: | Wiley |
Revista: | Ophthalmic and Physiological Optics |
Citação: | Martino, F., Amorim‐de‐Sousa, A., Fernandes, P., Castro‐Torres, J. J., & González‐Méijome, J. M. (2023, July 22). Neural binocular summation and the effect of defocus on the pattern electroretinogram and visual evoked potentials for different pupil sizes. Ophthalmic and Physiological Optics. Wiley. http://doi.org/10.1111/opo.13204 |
Resumo(s): | Purpose: To evaluate the influence of defocus and pupil size on subjective (visual acuity [VA]) and objective (electrophysiology) descriptors of human vision and their effect on binocular visual performance by means of neural binocular summation (BS). Methods: Fifteen healthy young subjects were recruited in this crossover study. Pattern electroretinogram (PERG) and visual evoked potentials (VEP) were measured under two levels of positive (+1.5 and +3.0 D) spherical and astigmatic defocus (axis 90°). Pupil size was controlled to reduce the inter-individual variability factor. Results: Low- and high-contrast VA showed poorer visual performance in the monocular versus the binocular condition. Positive BS (for VA) was higher with greater pupil size and higher levels of defocus. In the visual electrophysiology tests (i.e., VEP and PERG), peak time and amplitude were affected by pupil size and defocus. The increase in peak time was larger and the reduction in amplitude was more significant with greater levels of defocus and smaller pupil sizes. For the VEP, positive BS was found in all conditions, being stronger with larger amounts of defocus and pupil size (for the P100 amplitude). Significant negative correlations were observed between the P100 amplitude and VA BSs. Conclusion: Smaller pupil size and levels of defocus produced greater changes in cortical activity as evidenced by both the PERG and VEP. Considering these changes and the obtained positive BS, the mechanism could be initiated as early as the retinal processing stage, then being modulated and enhanced along the visual pathway and within the visual cortex. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/87519 |
DOI: | 10.1111/opo.13204 |
ISSN: | 0275-5408 |
e-ISSN: | 1475-1313 |
Versão da editora: | https://onlinelibrary.wiley.com/doi/10.1111/opo.13204 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CDF - OCV - Artigos/Papers (with refereeing) |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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5.5.190. MARTINO_23_OPO_Binocular summation pupil and defocus.pdf | 3,21 MB | Adobe PDF | Ver/Abrir |
Este trabalho está licenciado sob uma Licença Creative Commons