Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/76383
Título: | An overview of the current state of phage therapy for the treatment of biofilm-related infections |
Autor(es): | Pires, Diana Priscila Penso Meneses, Luciana Brandão, Ana Catarina Azeredo, Joana |
Data: | 28-Fev-2022 |
Editora: | Elsevier 1 |
Revista: | Current Opinion in Virology |
Citação: | Pires, Diana P.; Meneses, Luciana; Brandão, Ana Catarina; Azeredo, Joana, An overview of the current state of phage therapy for the treatment of biofilm-related infections. Current Opinion in Virology, 53(101209), 2022 |
Resumo(s): | Bacterial biofilms are involved in many chronic and difficult-to-treat infections. Phage therapy against infectious biofilms is becoming a promising strategy, as suggested by the increasing number of publications demonstrating the efficacy of phages against in vitro formed biofilms. However, the translation between in vitro results to in vivo phage therapy outcome is not straightforward due to the complexity of phage-biofilm interactions in clinical contexts. Here, we provide a critical overview of the in vitro studies of phages for biofilm control of clinical pathogens, followed by the major outcomes and lessons learned from the recently reported case studies (between 2018 and 2021) of phage therapy against biofilm-related infections. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/76383 |
DOI: | 10.1016/j.coviro.2022.101209 |
ISSN: | 1879-6257 |
Versão da editora: | https://doi.org/10.1016/j.coviro.2022.101209 |
Arbitragem científica: | yes |
Acesso: | Acesso restrito UMinho |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_55327_1.pdf Acesso restrito! | 726,6 kB | Adobe PDF | Ver/Abrir |