Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/70268
Título: | Nanostructured biopolymer/few-layer graphene freestanding films with enhanced mechanical and electrical properties |
Autor(es): | Silva, Cláudia Caridade, Sofia Glória Ferreira Cunha, Eunice Paula Freitas Sousa, Maria P. Rocha, Helena Mano, J. F. Paiva, M. C. Alves, N. M. |
Palavras-chave: | Biomedical applications Freestanding multilayered films Functionalized graphene Natural polymers |
Data: | 2018 |
Editora: | Wiley |
Revista: | Macromolecular Materials and Engineering |
Resumo(s): | In the present work, novel freestanding multilayered films based on chitosan (CHI), alginate (ALG), and functionalized few-layer graphene are developed through layer-by-layer assembly. First, functionalized few-layer graphene aqueous suspensions are prepared from graphite by a stabilizer-assisted liquid phase exfoliation process, using a pyrene derivative as stabilizer. Afterward, the films are produced and their physical, morphological, thermal, and mechanical properties are evaluated. Furthermore, their degradation and swelling profiles, as well as their biological behavior, are assessed. The incorporation of functionalized few-layer graphene results in films with a nanolayered structure, lower roughness than the control CHI/ALG films, and hydrophilic behavior. The mechanical characterization reveals an increase of the Young's modulus, ultimate tensile strength, and elongation at break due to the incorporation of the graphene derivative. A decrease in the electrical resistivity of the multilayered films is also observed. The biological assays reveal improved cytocompatibility toward L929 cells when functionalized few-layer graphene is incorporated in the CHI/ALG matrix. Therefore, these new graphene-reinforced multilayered films exhibit interesting properties and great potential for biomedical applications, particularly in wound healing and cardiac and bone tissue engineering. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/70268 |
DOI: | 10.1002/mame.201700316 |
ISSN: | 1438-7492 |
e-ISSN: | 1439-2054 |
Versão da editora: | https://onlinelibrary.wiley.com/doi/abs/10.1002/mame.201700316 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | IPC - Artigos em revistas científicas internacionais com arbitragem |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
---|---|---|---|---|
Macromolecular_Materials_and_Engineering 2018.pdf | 3,56 MB | Adobe PDF | Ver/Abrir |