Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/61482

TitleBlood cells separation and sorting techniques of passive microfluidic devices: From fabrication to applications
Author(s)Catarino, Susana O.
Rodrigues, Raquel O.
Pinho, Diana
Miranda, João M.
Minas, Graça
Lima, Rui Alberto Madeira Macedo
Keywordsmicrofluidics
red blood cells (RBCs)
microfabrication
polymers
separation and sorting techniques
Issue date2019
PublisherMultidisciplinary Digital Publishing Institute
JournalMicromachines
CitationCatarino, S.O.; Rodrigues, R.O.; Pinho, D.; Miranda, J.M.; Minas, G.; Lima, R. Blood Cells Separation and Sorting Techniques of Passive Microfluidic Devices: From Fabrication to Applications. Micromachines 2019, 10, 593.
Abstract(s)Since the first microfluidic device was developed more than three decades ago, microfluidics is seen as a technology that exhibits unique features to provide a significant change in the way that modern biology is performed. Blood and blood cells are recognized as important biomarkers of many diseases. Taken advantage of microfluidics assets, changes on blood cell physicochemical properties can be used for fast and accurate clinical diagnosis. In this review, an overview of the microfabrication techniques is given, especially for biomedical applications, as well as a synopsis of some design considerations regarding microfluidic devices. The blood cells separation and sorting techniques were also reviewed, highlighting the main achievements and breakthroughs in the last decades.
TypeArticle
URIhttp://hdl.handle.net/1822/61482
DOI10.3390/mi10090593
ISSN2072-666X
Publisher versionhttps://www.mdpi.com/2072-666X/10/9/593
Peer-Reviewedyes
AccessOpen access
Appears in Collections:CAlg - Artigos em revistas internacionais/Papers in international journals
DEM - Artigos em revistas de circulação internacional com arbitragem científica

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