Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/56695
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Campo DC | Valor | Idioma |
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dc.contributor.author | Martins, Artur J. | por |
dc.contributor.author | Gonçalves, Catarina | por |
dc.contributor.author | Amado, Isabel | por |
dc.contributor.author | Pastrana, Lorenzo M. | por |
dc.contributor.author | Cunha, Rosiane | por |
dc.contributor.author | Vicente, A. A. | por |
dc.contributor.author | Cerqueira, Miguel A. | por |
dc.date.accessioned | 2018-11-02T10:07:45Z | - |
dc.date.available | 2018-11-02T10:07:45Z | - |
dc.date.issued | 2018-10-23 | - |
dc.identifier.citation | Martins, Artur J.; Gonçalves, Catarina; Amado, Isabel; Pastrana, Lorenzo M.; Cunha, Rosiane; Vicente, António A.; Cerqueira, Miguel A., Digestion of beta-carotene loaded oleogels and transepithelial transport: in-vitro study. IUFoST 2018 - World Congress of Food Science and Technology. Mumbai, India, Oct 23-27, 2018. | por |
dc.identifier.uri | https://hdl.handle.net/1822/56695 | - |
dc.description.abstract | performance as carriers of bioactives, and their behaviour under gastrointestinal conditions has been scarcely studied. This work reports the behaviour of two distinct edible oleogels, loaded with a bioactive compound under in-vitro digestion conditions and assesses the bioactive bioacessibility and bioavailability of the bioactive compound. Method(s) and Results: Two types of gelation were used for the production of oleogels (i.e. single- and multi-component gelation), using respectively beeswax and a sterol mixture of gamma-oryzanol and beta-sitosterol (60X40 ratio). For both cases, long chain triglycerides were structured with 8% (w/w) of gelator and loaded with 0.1% (w/w) of beta-carotene. The recorded average hardness of sterol-based oleogels was approximately 4-fold higher than for beeswax oleogels. In-vitro digestion of oleogels was evaluated following the INFOGEST protocol. Bioacessibility of beta-carotene was of approx. 26% for sterol-based oleogels and close to 20% for beeswax-based oleogels. Afterwards, the digested samples were placed in contact with a monolayer of differentiated Caco-2 and HT-29-MTX cells, to determine the transepithelial transport of beta-carotene (bioavailability). Sterol gels favor the bioavailability of beta-carotene with an increase of 15% of bioactive transport over beeswax-based oleogels. No cytotoxicity of oleogels was detected. Conclusions: This study shows that the INFOGEST standard protocol is suitable for the in-vitro digestion evaluation of oleogels and that the bioacessibility of beta-carotene in these systems lays between 20 and 26 %. Oleogels are able to carry beta-carotene through the digestive process being enhanced by sterol gels. | por |
dc.language.iso | eng | por |
dc.rights | openAccess | por |
dc.title | Digestion of beta-carotene loaded oleogels and transepithelial transport: in-vitro study | por |
dc.type | conferencePoster | por |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | https://www.iufost2018.com/ | por |
dc.comments | CEB49067 | por |
oaire.citationConferencePlace | Mumbai, India | por |
dc.date.updated | 2018-11-01T22:30:04Z | - |
dc.subject.fos | Ciências Agrárias::Biotecnologia Agrária e Alimentar | por |
dc.description.publicationversion | info:eu-repo/semantics/publishedVersion | por |
sdum.conferencePublication | IUFoST 2018 - World Congress of Food Science and Technology | por |
Aparece nas coleções: | CEB - Painéis em Conferências / Posters in Conferences |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_49067_1.pdf | 2,78 MB | Adobe PDF | Ver/Abrir |