Utilize este identificador para referenciar este registo: http://hdl.handle.net/1822/56305

TítuloSilk fibroin-based hydrogels and scaffolds for osteochondral repair and regeneration
Autor(es)Ribeiro, Viviana Pinto
Pina, Sandra Cristina Almeida
Oliveira, J. M.
Reis, R. L.
Palavras-chaveHydrogels
Osteochondral regeneration
Scaffolds
Silk fibroin
Data2018
EditoraSpringer
RevistaAdvances in Experimental Medicine and Biology
CitaçãoRibeiro V. P., Pina S., Oliveira J. M., Reis R. L. Silk Fibroin-Based Hydrogels and Scaffolds for Osteochondral Repair and Regeneration, Osteochondral Tissue Engineering - Nanotechnology, Scaffolding-Related Developments and Translation, Advances in Experimental Medicine and Biology, pp. 305-325, doi:10.1007/978-3-319-76711-6_14, 2018
Resumo(s)Osteochondral lesions treatment and regeneration demands biomimetic strategies aiming physicochemical and biological properties of both bone and cartilage tissues, with long-term clinical outcomes. Hydrogels and scaffolds, appeared as assertive approaches to guide the development and structure of the new osteochondral engineered tissue. Moreover, these structuresalone or in combination with cells and bioactive molecules, bring the mechanical support after in vitro and in vivo implantation. Moreover, multilayered structures designed with continuous interfaces, furnish appropriate features of the cartilage and subchondral regions, namely microstructure, composition, and mechanical properties. Owing the potential as scaffolding materials, natural and synthetic polymers, bioceramics, and composites, have been employed. Particularly, significance is attributed to the natural-based biopolymer silk ï¬ broin from the Bombyx mori silkworm, considering its unique mechanical and biological properties. The significant studies on silk fibroin-based structures, namely hydrogels and scaffolds, towards bone, cartilage, and osteochondral tissue repair and regeneration are overviewed herein. The developed biomimetic strategies, processing methodologies, and final properties of the structures are summarized and discussed in depth.
TipobookPart
URIhttp://hdl.handle.net/1822/56305
ISBN978-3-319-76710-9
DOI10.1007/978-3-319-76711-6_14
ISSN0065-2598
Versão da editorahttps://link.springer.com/chapter/10.1007/978-3-319-76711-6_14
Arbitragem científicano
AcessorestrictedAccess
Aparece nas coleções:3B’s - Capítulos de Livros/Book Chapters

Ficheiros deste registo:
Ficheiro Descrição TamanhoFormato 
19320-SF hydrogels and scaffolds.pdf1,15 MBAdobe PDFVer/Abrir  Solicitar cópia ao autor!

Partilhe no FacebookPartilhe no TwitterPartilhe no DeliciousPartilhe no LinkedInPartilhe no DiggAdicionar ao Google BookmarksPartilhe no MySpacePartilhe no Orkut
Exporte no formato BibTex mendeley Exporte no formato Endnote Adicione ao seu Currículo DeGóis