Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/50460

TitleLactobacillus crispatus represses vaginolysin expression by BV associated Gardnerella vaginalis and reduces cell cytotoxicity
Author(s)Castro, Joana
Martins, A.
Rodrigues, M. Elisa
Cerca, Nuno
KeywordsBacterial vaginosis
G. vaginalis
L. crispatus
Vaginolysin
Sialidase
Issue dateApr-2018
PublisherElsevier
JournalAnaerobe
CitationCastro, Joana; Martins, A.; Rodrigues, M. Elisa; Cerca, Nuno, Lactobacillus crispatus represses vaginolysin expression by BV associated Gardnerella vaginalis and reduces cell cytotoxicity. Anaerobe, 50, 60-63, 2018
Abstract(s)Using a chemically-defined medium simulating genital tract secretions, we have shown that pre-adhering Lactobacillus crispatus to Hela epithelial cells reduced cytotoxicity caused by Gardnerella vaginalis. This effect was associated to the expression of vaginolysin and was specific to L. crispatus interference, as other vaginal facultative anaerobes had no protective effect.
TypeArticle
URIhttp://hdl.handle.net/1822/50460
DOI10.1016/j.anaerobe.2018.01.014
ISSN1075-9964
e-ISSN1095-8274
Publisher versionhttp://www.journals.elsevier.com/anaerobe/
Peer-Reviewedyes
AccessOpen access
Appears in Collections:CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

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