Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/47598

TitleInter observer and intraobserver repeatability of lipid layer pattern evaluation by two experienced observers
Author(s)García-Resúa, Carlos
Pena-Verdeal, Hugo
Lira, Madalena
Penedo, Manuel
Giraldez, Maria J.
Yebra-Pimentel Vilar, Eva
KeywordsTear film
Lipid layer thickness
Lipid layer pattern
Tearscope
Issue date2013
PublisherSPIE
JournalProceedings of SPIE
Abstract(s)The lipid layer plays a major role in limiting evaporation of the tear film. Based on interference phenomena, there is a test directed to lipid layer pattern (LLP) evaluation, but is affected by subjective interpretation of the patterns. The aim of this study is to compare the LLP evaluation between two experienced observers on a group of healthy patients. Furthermore, the observers re-evaluated the same images in order to check their individual repeatability. LLP was examined using a Tearscope-plus (Keeler, Windsor, UK) attached to a slit lamp. Tear film was ecorded by a Topcon DV-3 digital camera video and LLP images were captured. This yielded 124 LLP images that were categorized (based on Guillon’s schema) by two expert observers in two sessions separated by one month. Interobserver repeatability and intraobserver repeatability between both sessions were studied by using Cohen’s kappa coefficient. Comparing LLP categorization between both observers, Cohen's kappa coefficient was 0.615 and 0.633 for first and second session, respectively. When comparing LLP categorization by the same observer between both sessions, Cohen's kappa coefficient was 0.770 and 0.812 for Observer 1 and Observer 2. These results indicate substantial correlation in all cases [range of 0.61–0.80]. The most frequent misinterpretations were between open and closed meshwork and Wave and closed meshwork patterns. Although substantial correlation was found between categorizations of experienced observers, misinterpretation of the patters may appear even in the same observer. Some misinterpretations between adjacent patterns could be palliated by including intermediate patterns between those categories.
TypeconferencePaper
URIhttp://hdl.handle.net/1822/47598
ISBN9780819496010
DOI10.1117/12.2030432
ISSN0277-786X
e-ISSN1996-756X
Peer-Reviewedyes
AccessclosedAccess
Appears in Collections:CDF - OCV - Artigos/Papers (with refereeing)

Files in This Item:
File Description SizeFormat 
Inter Observer and intraobserver repeatability of Lipid layer.pdf513,43 kBAdobe PDFView/Open    Request a copy!

Partilhe no FacebookPartilhe no TwitterPartilhe no DeliciousPartilhe no LinkedInPartilhe no DiggAdicionar ao Google BookmarksPartilhe no MySpacePartilhe no Orkut
Exporte no formato BibTex mendeley Exporte no formato Endnote Adicione ao seu Currículo DeGóis